Imipramine EP Impurity B HCl CAS 58262-51-4
| CAS No. | 58262-51-4 |
| Molecular Formula | C19H22N2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Imipramine EP Impurity B HCl (CAS 58262-51-4, C19H22N2HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C19H22N2HCl, Imipramine EP Impurity B HCl contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 314.86 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C19H22N2 HCl |
| Molecular Weight | 314.86 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Imipramine Standards
- Imipramine Pamoate (CAS 10075-24-8)
- Imipramine-D3 maleate (CAS 112898-42-7)
- Imipramine Hydrochloride (CAS 113-52-0)
- Imipramine N-Oxide (CAS 1215681-42-7)
- Imipramine N-β-D-Glucuronide (CAS 165602-94-8)
- Imipramine impurity C (CAS 2307-88-2)
- Imipramine EP Impurity B (CAS 303-54-8)
- Imipramine EP Impurity A (CAS 50-47-5)
Recommended Standards
- Letrozole Impurity 31 (CAS CATO-C4X-182931)
- Propofol Impurity 52 (CAS CATO-C4X-147352)
- Etomidate Impurity 33 (CAS CATO-C4X-188433)
- tert-Butyl 4-(2-oxoethyl)piperazine-1-carboxylate (CAS 945953-41-3)
- 5,5'-([1,1'-Binaphthalene]-4,4'-diyl)diisophthalic acid (CAS 2413724-98-6)
- (1S,3R)-3-methoxycyclopentane-1-carboxylic acid (CAS 886026-75-1)
- 3-(2,4,6-Trimethylbenzyl)piperazin-2-one (CAS 1246548-33-3)
- 5-Bromo-N,2-dimethylpyrimidin-4-amine (CAS 1256818-11-7)
- 4,4,5,5-Tetramethyl-2-(2-methyl-4-(tetrahydro-2H-pyran-4-yl)phenyl)-1,3,2-dioxaborolane (CAS 2223039-63-0)
- Semaglutide impurity 203 (CAS CATO-C4X-2226203)
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