Remdesivir Impurity 39 CAS 58479-61-1
| CAS No. | 58479-61-1 |
| Molecular Formula | C16H19ClSi |
| Molecular Weight | 274.86 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Remdesivir Impurity 39 (CAS 58479-61-1) is a certified pharmaceutical impurity reference standard with the molecular formula C16H19ClSi and a molecular weight of 274.86 g/mol.
Remdesivir Impurity 39 (C16H19ClSi) contains chlorine substitution, a polycyclic aromatic system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H19ClSi |
| Molecular Weight | 274.86 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | Cl-containing |
Related Remdesivir Standards
- Remdesivir Impurity 44 (CAS 1187550-21-5)
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- Remdesivir Impurity 17 (CAS CATO-C4X-210017)
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- Remdesivir Impurity 25 (CAS CATO-C4X-210025)
Recommended Standards
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