4-(Trifluoromethyl)cyclohexylamine CAS 58665-70-6
| CAS No. | 58665-70-6 |
| Molecular Formula | C7H12F3N |
| Molecular Weight | 167.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(Trifluoromethyl)cyclohexylamine is closely related to fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-(Trifluoromethyl)cyclohexylamine (CAS 58665-70-6) is a high-purity analytical reference standard with the molecular formula C7H12F3N and a molecular weight of 167.17 g/mol.
The molecular framework of 4-(Trifluoromethyl)cyclohexylamine (C7H12F3N) is characterized by fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-(Trifluoromethyl)cyclohexylamine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H12F3N |
| Molecular Weight | 167.17 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethyl Standards
- trans-4-(trifluoromethyl)cyclohexanamine (CAS 1073266-02-0)
- 4-Methyl-2-(trifluoromethyl)piperidine (CAS 1269151-53-2)
- 2-Methyl-6-(trifluoromethyl)piperidine (CAS 1343143-23-6)
- 2-Methyl-3-(trifluoromethyl)piperidine (CAS 1344061-79-5)
- 1-(Trifluoromethyl)cyclohexan-1-amine (CAS 134424-35-4)
- 2-Methyl-5-(trifluoromethyl)piperidine (CAS 1344335-43-8)
- 2-Methyl-2-(trifluoromethyl)piperidine (CAS 1432680-53-9)
- (3-(Trifluoromethyl)cyclopentyl)methanamine (CAS 1461706-09-1)
Recommended Standards
- 4-(Dimethylamino)pyrimidine-5-carboxylic acid (CAS 773098-81-0)
- 4,4-Difluoro-1-(fluoromethyl)cyclohexan-1-amine (CAS 2228506-41-8)
- 4-(Aminomethyl)-2-nitroaniline (CAS 79556-69-7)
- 4,5,6,7-Tetrahydro-1H-benzo[d][1,2,3]triazole-6-carboxylic acid (CAS 33062-47-4)
- 3-(5-Formylthiophen-3-yl)benzoic acid (CAS 893737-11-6)
- 8-Bromo-1-methyl-3H-pyridazino[4,5-b]indol-4(5H)-one (CAS 1415653-08-5)
- (R)-1-(2-(Diphenylphosphanyl)phenyl)-N-methylethan-1-amine (CAS 1332500-23-8)
- 2-(2,6-Dimethylmorpholin-4-yl)-3-methyl-butanoic acid hydrochloride (CAS 1214108-42-5)
- 2-(n-Methyl4-chloro-2-fluorobenzenesulfonamido)acetic acid (CAS 1097822-15-5)
- Perfluoro(2-methyl-3-oxahexanoyl) Fluoride (CAS 2062-98-8)
- 1-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-yl)ethanone (CAS 2223045-63-2)
- 5-Fluoro-1H-pyrrolo[2,3-b]pyridine-4-carboxylic acid (CAS 1228666-41-8)
- Edoxaban impurity 133 (CAS CATO-C4X-1063133)
- FLAG Epitope Peptide (CAS 98849-88-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com