Ethyl 4,7-dichloro-8-methylquinoline-3-carboxylate CAS 58666-08-3

Purity 97%+In StockPharmaceutical Standards
CAS No.58666-08-3
Molecular FormulaC13H11Cl2NO2
Molecular Weight284.14 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Ethyl 4,7-dichloro-8-methylquinoline-3-carboxylate CAS 58666-08-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 284.14 g/mol gives Ethyl 4,7-dichloro-8-methylquinoline-3-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Ethyl 4,7-dichloro-8-methylquinoline-3-carboxylate (CAS 58666-08-3), a certified reference material (molecular formula C13H11Cl2NO2, MW 284.14 g/mol) for analytical method development and quality control.

The molecular framework of Ethyl 4,7-dichloro-8-methylquinoline-3-carboxylate (C13H11Cl2NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), Ethyl 4,7-dichloro-8-methylquinoline-3-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC13H11Cl2NO2
Molecular Weight284.14 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1973
Halogen ContentCl-containing
Nitrogen Atoms1

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