Misoprostol EP Impurity E CAS 58717-36-5
| CAS No. | 58717-36-5 |
| Molecular Formula | C22H38O5 |
| Molecular Weight | 382.53 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Misoprostol EP Impurity E (CAS 58717-36-5), a pharmacopoeial impurity reference standard (molecular formula C22H38O5, MW 382.53 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Misoprostol EP Impurity E (C22H38O5) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Misoprostol EP Impurity E meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H38O5 |
| Molecular Weight | 382.53 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
Related Misoprostol Standards
- Misoprostol EP Impurity A (mixture of isomers) (CAS 1788085-78-8)
- Misoprostol Impurity 1 (CAS CATO-C4X-14591)
- Misoprostol EP Impurity B (CAS CATO-C4X-14592)
- Misoprostol (CAS 59122-46-2)
- Misoprostol-d5 (CAS 1337917-44-8)
- Misoprostol Acid (CAS 112137-89-0)
- Misoprostol Acid (Mixture of Diastereomers) (CAS 66792-31-2)
- Misoprostol Impurity 7 (CAS CATO-C4X-14597)
Recommended Standards
- Prostaglandin Impurity 24 (CAS CATO-C4X-199624)
- Carboprost Methyl Ester (CAS 35700-21-1)
- 4-tert-Octylphenol tetraethoxylate (CAS 2315-63-1)
- Carboprost Impurity 4 (CAS 62776-96-9)
- Brivaracetam Impurity 15 (CAS 2432911-32-3)
- Opicapone impurity 30 (CAS CATO-C4X-240430)
- Ergocalciferol EP Impurity D (CAS 469-06-7)
- 1-Butyl-4,4-dimethyl-1,4,5,6-tetrahydrocyclopenta[b]pyrrole (CAS 227018-86-2)
- 5-Bromo-2-(methylamino)nicotinic acid (CAS 610279-81-7)
- 4-(tert-Butoxy)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 2223012-89-1)
- 2-(4-methyl-1,3-thiazol-2-yl)morpholine (CAS 1258650-34-8)
- 4-Chloro-2-fluorophenyl isothiocyanate (CAS 68034-69-5)
- tert-Butyl 4-(2-aminoethyl)-4-(2-fluorophenyl)-1-piperidinecarboxylate (CAS 1823490-65-8)
- Neuropeptide K, porcine (CAS 106441-70-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com