H-4-Nitro-Phe-OEt · HCl CAS 58816-66-3
| CAS No. | 58816-66-3 |
| Molecular Formula | C11H14N2O4 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
H-4-Nitro-Phe-OEt · HCl (CAS 58816-66-3), molecular formula C11H14N2O4HCl and molecular weight 274.70 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, H-4-Nitro-Phe-OEt · HCl is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 274.70 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H14N2O4 HCl |
| Molecular Weight | 274.70 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- 2,4-dichloro-7-fluoro-pyrido[4,3-d]pyrimidine (CAS 2386486-39-9)
- 2-(Diethylamino)ethyl 2-cyclohexyl-2-phenylacetate (CAS 1679-76-1)
- tert-butyl 2-(3-amino-2-oxopyrrolidin-1-yl)-2-phenylacetate (CAS 1796925-30-8)
- Dabigatran Impurity 69 (CAS 41263-74-5)
- 5-(3-Chlorophenyl)oxazole-2(3H)-thione (CAS 950272-78-3)
- 1-(2-chloro-3-fluorophenyl)cyclopropan-1-ol (CAS 1504931-98-9)
- (R)-2-Amino-1-(4-(tert-butyl)phenyl)ethanol (CAS 1568036-89-4)
- 1-(1-Ethyl-5-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)ethan-1-one (CAS 1312137-42-0)
- Ethyl 4-(6-oxopiperidin-3-yl)benzoate (CAS 281233-72-5)
- Liraglutide-d8 Tritrifluoroacetate (CAS CATO-C4X-199223)
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