Papaverine EP Impurity C HCl (3,4-Dihydropapaverine HCl) CAS 5884-22-0
| CAS No. | 5884-22-0 |
| Molecular Formula | C20H23NO4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Papaverine EP Impurity C HCl (3,4-Dihydropapaverine HCl) (CAS 5884-22-0), a pharmacopoeial impurity reference standard (molecular formula C20H23NO4HCl, MW 377.86 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Papaverine EP Impurity C HCl (3,4-Dihydropapaverine HCl) (C20H23NO4HCl) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 377.86 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Papaverine EP Impurity C HCl (3,4-Dihydropapaverine HCl) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H23NO4 HCl |
| Molecular Weight | 377.86 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Papaverine Standards
- Papaverine-d3 Hydrochloride (CAS 113718-66-4)
- Papaverine Impurity 37 (CAS 1207386-32-0)
- Papaverine Hydrochloride - Impurity E (CAS 13074-31-2)
- Papaverine EP Impurity F (CAS 139-76-4)
- Papaverine Impurity 35 (CAS 16637-56-2)
- Papaverine Impurity 14 Hcl (CAS 18694-10-5（free base）)
- Papaverine Impurity 17 (CAS 18783-43-2)
- Papaverine Impurity 2 (CAS 18813-60-0)
Recommended Standards
- Orforglipron Impurity 115 (CAS CATO-C4X-3234115)
- Edoxaban Impurity 36 (1S,2R,4S) (CAS 480452-36-6)
- Benidipine Impurity 41 DiHCl (CAS 144243-28-7(free base))
- (E)-N-(3-((5-Chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-3-(4-(dimethylamino)but-2-enamido)benzamide (CAS 1604810-84-5)
- Daptomycin Impurity 56 (CAS CATO-C4X-137856)
- 2-Chloro-6-isopropylnicotinic acid (CAS 166331-65-3)
- Phenazin-2-ol (CAS 4190-95-8)
- Menaquinone 5 (CAS 1182-68-9)
- 3-Amino-1-(4-bromophenyl)azetidin-2-one hydrochloride (CAS 1803566-69-9)
- Tau Peptide (268-282) trifluoroacetate salt (CAS 330456-37-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com