8-Chloro-2-(4-ethylphenyl)quinoline-4-carbohydrazide CAS 588711-80-2
| CAS No. | 588711-80-2 |
| Molecular Formula | C18H16ClN3O |
| Molecular Weight | 325.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
8-Chloro-2-(4-ethylphenyl)quinoline-4-carbohydrazide (CAS 588711-80-2), molecular formula C18H16ClN3O and molecular weight 325.79 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 8-Chloro-2-(4-ethylphenyl)quinoline-4-carbohydrazide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 325.79 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 8-Chloro-2-(4-ethylphenyl)quinoline-4-carbohydrazide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H16ClN3O |
| Molecular Weight | 325.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 5-Chloro-N-(5-(thiophen-2-ylmethyl)-1,3,4-oxadiazol-2-yl)thiophene-2-carboxamide (CAS 1020977-39-2)
- 2-Chloro-N-[4-(1-cyanocyclopentyl)phenyl]-3-pyridinecarboxamide (CAS 1158560-99-6)
- 4-Chloro-2-(((4-phenoxyphenyl)amino)methyl)phenol (CAS 1223887-94-2)
- 2-{2-[(5-Chloro-1,2,4-thiadiazol-3-yl)sulfanyl]ethyl}-2,3-dihydro-1h-isoindole-1,3-dione (CAS 1326815-58-0)
- 7-chloro-2-ethyl-4,4-dioxo-1,2,3-trihydro-4-thiaquinazoline-6-sulfonamide (CAS 1824-58-4)
- (E)-[(5-Chloro-2-phenyl-1H-imidazol-4-yl)methylidene][(4-methoxyphenyl)methyl]amine (CAS 338392-68-0)
- 2-(5-Chloro-8-isopropoxyquinolin-7-yl)benzaldehyde (CAS 648897-06-7)
- 2-Chloro-3-((4-isopropylphenyl)amino)naphthalene-1,4-dione (CAS 763130-56-9)
Recommended Standards
- 7-Chloro-3,8-dimethyl-2-(4-methylphenyl)quinoline-4-carboxylic acid (CAS 862661-17-4)
- 8-Chloro-2-(4-isopropylphenyl)quinoline-4-carboxylic acid (CAS 862661-15-2)
- 7-Chloro-2-(4-ethylphenyl)-8-methylquinoline-4-carboxylic acid (CAS 588711-30-2)
- 8-Chloro-2-(4-propylphenyl)quinoline-4-carboxylic acid (CAS 588676-12-4)
- N-(2-Methoxyphenyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide (CAS 1704069-54-4)
- 1-(6-Chloro-1-(2-ethoxyethyl)-1H-benzo[d]imidazol-2-yl)ethan-1-ol (CAS 1243677-44-2)
- (4-(Benzyloxy)phenyl)(phenyl)methanone (CAS 54589-41-2)
- 2-(furan-2-yl)pyrazine (CAS 32736-95-1)
- 3-Chloro-4-cyclopropoxy-5-methoxypyridine (CAS 1243457-34-2)
- 1-Benzylpiperidine-2-carbaldehyde (CAS 157634-01-0)
- 2,4-Dibromo-3,6-difluorophenylacetonitrile (CAS 1806350-81-1)
- N-(4-aminophenyl)-N’-(2-methoxyethyl)urea (CAS 1087784-17-5)
- 3-(4-Bromophenyl)-6-methyl-2H-benzo[b][1,4]oxazine (CAS 351003-33-3)
- Semaglutide Impurity 152 xTFA (CAS CATO-C4X-2226152)
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