n-[4-(chloromethyl)-1,3-thiazol-2-yl]-n-phenylacetamide CAS 58905-44-5

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including n-[4-(chloromethyl)-1,3-thiazol-2-yl]-n-phenylacetamide.

CATO supplies n-[4-(chloromethyl)-1,3-thiazol-2-yl]-n-phenylacetamide (CAS 58905-44-5), a certified reference material (molecular formula C12H11ClN2OS, MW 266.75 g/mol) for analytical method development and quality control.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution, n-[4-(chloromethyl)-1,3-thiazol-2-yl]-n-phenylacetamide is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 266.75 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), n-[4-(chloromethyl)-1,3-thiazol-2-yl]-n-phenylacetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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