4-Chloro-3-(piperidine-1-sulfonyl)benzoic acid CAS 59210-74-1
| CAS No. | 59210-74-1 |
| Molecular Formula | C12H14ClNO4S |
| Molecular Weight | 303.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Chloro-3-(piperidine-1-sulfonyl)benzoic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4-Chloro-3-(piperidine-1-sulfonyl)benzoic acid (CAS 59210-74-1), a certified reference material (molecular formula C12H14ClNO4S, MW 303.76 g/mol) for analytical method development and quality control.
Structurally, 4-Chloro-3-(piperidine-1-sulfonyl)benzoic acid (C12H14ClNO4S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 303.76 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Chloro-3-(piperidine-1-sulfonyl)benzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H14ClNO4S |
| Molecular Weight | 303.76 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 2-Chloro-5-(piperidine-1-sulfonyl)benzoic acid (CAS 109029-95-0)
- 5-Chloro-3-(phenylthio)-1H-indole-2-carboxylic acid (CAS 118427-38-6)
- 2-Chloro-1-(6-(ethylsulfonyl)-2,3-dihydro-4H-benzo[b][1,4]oxazin-4-yl)ethan-1-one (CAS 1198475-23-8)
- 1-(2-Chloro-6-fluorobenzyl)-1,3,4,5-tetrahydro-2H-benzo[b]azepin-2-one (CAS 303987-97-5)
- 1-(2-Chloro-6-fluorobenzyl)-N-ethyl-1H-benzo[d]imidazol-2-amine (CAS 866137-42-0)
- 2-[(2-Chloro-1,3-thiazol-5-yl)methoxy]naphthalene-1-carbaldehyde (CAS 672950-02-6)
- 2-Chloro-11-methyldibenzo[b,f][1,4]thiazepine-8-carboxylic acid (CAS 897771-53-8)
- 2-Chloro-3-((thiophen-2-ylmethyl)amino)naphthalene-1,4-dione (CAS 331462-34-1)
Recommended Standards
- 4-Azetidinomethyl-4-chloro-3-fluorobenzophenone (CAS 898756-75-7)
- 4-Methoxy-3-(pyrrolidin-1-ylcarbonyl)-benzenesulfonyl chloride (CAS 952946-98-4)
- 4-Azetidinomethyl-3-chloro-5-fluorobenzophenone (CAS 898756-91-7)
- 6-Chloro-2-(5-methylthiophen-2-yl)quinoline-4-carboxylic acid (CAS 438216-95-6)
- (2E)-1-(4-Methoxyphenyl)-3-(2,3,4-trimethoxyphenyl)prop-2-en-1-one (CAS 1639856-65-7)
- 4-Methyl-4-phenylpentane-2-sulfonyl chloride (CAS 1017159-52-2)
- 2-Amino-N-[3-(morpholin-4-yl)propyl]benzamide (CAS 13666-71-2)
- 2-(2-(2-(2-(Quinolin-8-yloxy)ethoxy)ethoxy)ethoxy)ethanol (CAS 77544-61-7)
- 3,3-difluorocyclobutanesulfonic acid (CAS 1310795-42-6)
- 4-(2-Oxo-1-pyrrolidinyl)phenylboronic Acid Pinacol Ester (CAS 1003309-09-8)
- 3,5,5-Trimethylcyclohex-2-en-1-amine (CAS 54920-40-0)
- Methyl 3-Methoxy-4-methylbenzoate (CAS 3556-83-0)
- Cabozantinib Impurity 33 (CAS 849217-48-7)
- (Ser(PO?H?)3??·???)-Tau Peptide (379-408) trifluoroacetate salt (CAS 2022956-60-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com