2-Amino-5-bromo-4-methylnicotinic acid hydrochloride CAS 59414-89-0
| CAS No. | 59414-89-0 |
| Molecular Formula | C7H7BrN2O2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Amino-5-bromo-4-methylnicotinic acid hydrochloride (CAS 59414-89-0), molecular formula C7H7BrN2O2HCl and molecular weight 267.51 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system, 2-Amino-5-bromo-4-methylnicotinic acid hydrochloride is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 267.51 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H7BrN2O2 HCl |
| Molecular Weight | 267.51 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
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Recommended Standards
- 3-[(4-Methylbenzyl)sulfanyl]-1-(2-methylphenyl)-6,7-dihydro-5H-cyclopenta[c]pyridine-4-carbonitrile (CAS 439107-25-2)
- 2-Carboxyphenylboronic acid dihydrate (CAS 1257650-88-6)
- (E)-3-chloro-2-(2-(thiophen-2-ylmethylene)hydrazinyl)-5-(trifluoromethyl)pyridine (CAS 338795-24-7)
- 5-fluoro-2-(oxiran-2-yl)pyridine (CAS 1548860-89-4)
- 1-(2-Oxo-2-phenylethyl)pyridin-1-ium bromide (CAS 16883-69-5)
- 2-(Pyridin-2-yl)-5-(trifluoromethyl)-2H-1,2,3-triazole-4-carboxylic acid (CAS 1708250-24-1)
- tert-Butyl 3-(4-nitro-1H-pyrazol-1-yl)pyrrolidine-1-carboxylate (CAS 1056024-38-4)
- 3-Amino-3-(3-nitrophenyl)propanoicacid (CAS 5678-47-7)
- 2-Methyl-1H-indole-3-sulfonyl chloride (CAS 1216116-64-1)
- HA Peptide (CAS 92000-76-5)
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