Ethyl 6-methyl-2-oxo-4-(thiophen-2-yl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate CAS 5948-72-1
| CAS No. | 5948-72-1 |
| Molecular Formula | C12H14N2O3S |
| Molecular Weight | 266.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ethyl 6-methyl-2-oxo-4-(thiophen-2-yl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Ethyl 6-methyl-2-oxo-4-(thiophen-2-yl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate (CAS 5948-72-1) is a high-purity analytical reference standard with the molecular formula C12H14N2O3S and a molecular weight of 266.32 g/mol.
The molecular framework of Ethyl 6-methyl-2-oxo-4-(thiophen-2-yl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate (C12H14N2O3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Ethyl 6-methyl-2-oxo-4-(thiophen-2-yl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H14N2O3S |
| Molecular Weight | 266.32 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Recommended Standards
- Ethyl 4-[(cyanomethyl)(methyl)amino]-2-(methylsulfanyl)-5-pyrimidinecarboxylate (CAS 860788-08-5)
- Methyl (6-propoxybenzo[d]thiazol-2-yl)carbamate (CAS 61570-90-9)
- Ethyl 2-(5,6-dimethyl-4-oxothieno[2,3-d]pyrimidin-3(4h)-yl)acetate (CAS 369397-75-1)
- Methyl 2-(2-cyanoacetamido)-4-ethyl-5-methylthiophene-3-carboxylate (CAS 514219-83-1)
- 2-Pyrrolidinomethyl-3-trifluoromethylbenzophenone (CAS 898774-81-7)
- 4-Isobutyl-2-phenyloxazol-5(4H)-one (CAS 25163-98-8)
- (2-Amino-4-(trifluoromethyl)thiazol-5-yl)(phenyl)methanone (CAS 123556-64-9)
- 2,2-dioxo-1,3-dihydro-2$l^{6}-benzothiophene-5-sulfonamide (CAS 72007-45-5)
- 3-[5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl]propanoic acid (CAS 933685-27-9)
- 5-Nitro-1,2,3,4-tetrahydrocyclopenta[b]indole (CAS 13687-73-5)
- (S)-1-Methyl-2-phenylaziridine (CAS 33815-65-5)
- Venlafaxine Impurity 4 (CAS 29903-09-1)
- (3S,4R,5R)-5-Methyl-3,4-piperidinediol hydrochloride (CAS 176485-25-9)
- (Des-Thr?)-Glucagon trifluoroacetate salt (CAS 1802078-27-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com