4-(5-Amino-1,3,4-thiadiazol-2-yl)phenol CAS 59565-53-6

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

4-(5-Amino-1,3,4-thiadiazol-2-yl)phenol (CAS 59565-53-6), molecular formula C8H7N3OS and molecular weight 193.23 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 4-(5-Amino-1,3,4-thiadiazol-2-yl)phenol (C8H7N3OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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