tert-Butyl (5-ethynylquinolin-8-yl) carbonate CAS 596135-26-1

Purity 97%+In StockPharmaceutical Standards
CAS No.596135-26-1
Molecular FormulaC16H15NO3
Molecular Weight269.30 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

tert-Butyl (5-ethynylquinolin-8-yl) carbonate CAS 596135-26-1 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 269.30 g/mol gives tert-Butyl (5-ethynylquinolin-8-yl) carbonate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

tert-Butyl (5-ethynylquinolin-8-yl) carbonate (CAS 596135-26-1), molecular formula C16H15NO3 and molecular weight 269.30 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of tert-Butyl (5-ethynylquinolin-8-yl) carbonate (C16H15NO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), tert-Butyl (5-ethynylquinolin-8-yl) carbonate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC16H15NO3
Molecular Weight269.30 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1984
Nitrogen Atoms1

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