2-(Hydroxymethyl)-5-methoxyphenol CAS 59648-29-2

Purity 97%+In StockPharmaceutical Standards
CAS No.59648-29-2
Molecular FormulaC8H10O3
Molecular Weight154.16 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(Hydroxymethyl)-5-methoxyphenol CAS 59648-29-2 chemical structure

Description

The occurrence of 2-(Hydroxymethyl)-5-methoxyphenol is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

2-(Hydroxymethyl)-5-methoxyphenol (CAS 59648-29-2) is a high-purity analytical reference standard with the molecular formula C8H10O3 and a molecular weight of 154.16 g/mol.

The molecular framework of 2-(Hydroxymethyl)-5-methoxyphenol (C8H10O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(Hydroxymethyl)-5-methoxyphenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H10O3
Molecular Weight154.16 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1974

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