2-Phenylquinoline-4-carbonyl chloride CAS 59661-86-8
| CAS No. | 59661-86-8 |
| Molecular Formula | C16H11NO2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 2-Phenylquinoline-4-carbonyl chloride (CAS 59661-86-8), a certified reference material (molecular formula C16H11NO2Cl, MW 284.72 g/mol) for analytical method development and quality control.
The molecular framework of 2-Phenylquinoline-4-carbonyl chloride (C16H11NO2Cl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures 2-Phenylquinoline-4-carbonyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H11NO2 Cl |
| Molecular Weight | 284.72 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Phenylquinoline Standards
- 2-Methyl-4-phenylquinoline-3-carboxylic acid (CAS 10265-84-6)
- 8-Methyl-2-phenylquinoline-4-carboxylic Acid (CAS 107027-34-9)
- 2-Phenylquinoline-5-carboxylic acid (CAS 11139-62-1)
- 6-Ethyl-2-phenylquinoline-4-carbonyl chloride (CAS 1160261-02-8)
- 2-Phenylquinoline-4-carbaldehyde (CAS 117839-38-0)
- 6-Methyl-2-(2-phenylquinoline-4-carboxamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide hydrochloride (CAS 1217055-59-8)
- 3-Methyl-4-phenylquinoline-6-carboxylic acid (CAS 1264210-70-9)
- 2-Phenylquinoline-3,4-dicarboxylic acid (CAS 133505-06-3)
Recommended Standards
- {4-Chloro-2-[2-(morpholin-4-yl)ethoxy]phenyl}boronic acid (CAS 2377605-74-6)
- 4-[(2,5-Dichlorophenyl)methyl]piperidine (CAS 286469-96-3)
- 1-Cyclopentyl-3-iodopyrazolo[3,4-d]pyrimidin-4-amine (CAS 330794-31-5)
- 4-Benzyloxy-3-methylphenylboronic Acid (CAS 338454-30-1)
- Potassium 2-((phosphonomethyl)amino)acetate (CAS 39600-42-5)
- N6-(2-Aminoethyl)-3-nitro-2,6-pyridinediamine (CAS 252944-01-7)
- 5,6,7,8-Tetrahydroquinolin-7-ol (CAS 160240-07-3)
- 2-[(E)-2-(Dimethylamino)ethenyl]-4-(4-heptylphenyl)-5-oxo-5H-indeno[1,2-b]pyridine-3-carbonitrile (CAS 551930-89-3)
- Acetic acid, 2-chloro-2,2-difluoro-, silver(1+) salt (1:1) (CAS 2923-14-0)
- A-18-F-NH2; Morphine Modulating Neuropeptide (CAS 99588-52-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com