6-methylpiperazin-2-one CAS 59701-83-6
| CAS No. | 59701-83-6 |
| Molecular Formula | C5H10N2O |
| Molecular Weight | 114.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6-methylpiperazin-2-one is closely related to an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 6-methylpiperazin-2-one (CAS 59701-83-6), a certified reference material (molecular formula C5H10N2O, MW 114.15 g/mol) for analytical method development and quality control.
The molecular framework of 6-methylpiperazin-2-one (C5H10N2O) is characterized by an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-methylpiperazin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H10N2O |
| Molecular Weight | 114.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1974 |
| Nitrogen Atoms | 2 |
Related methylpiperazin Standards
- (5S)-5-methylpiperazin-2-one (CAS 1240583-20-3)
- (5R)-5-methylpiperazin-2-one (CAS 1240589-51-8)
- (R)-6-Methylpiperazin-2-one (CAS 1240589-57-4)
- (6S)-6-methylpiperazin-2-one (CAS 323592-68-3)
- (S)-3-Methylpiperazin-2-one (CAS 78551-38-9)
- 5-methylpiperazin-2-one (CAS 907973-06-2)
- (4-Methylpiperazin-1-yl)methanimine (CAS 116833-32-0)
- (1-Methylpiperazin-2-yl)methanamine (CAS 131922-03-7)
Recommended Standards
- 5-methylpyridazin-3(2H)-one (CAS 54709-94-3)
- 6-oxa-3-azabicyclo[3.1.1]heptan-3-amine (CAS 2646592-56-3)
- Acetone acetylhydrazone (CAS 3742-63-0)
- 5-methyl-1H-pyrazole-3-carbaldehyde (CAS 3273-44-7)
- 3-(hydroxymethyl)cyclopentan-1-one (CAS 64646-09-9)
- 4-Chloro-5H-pyrimido[5,4-b]indole hydrochloride (CAS 107400-97-5)
- GNE 7915 (CAS 1351761-44-8)
- (3R)-3-amino-3-(2-anthryl)propanoic acid (CAS 1269844-88-3)
- 3-Morpholino-4-(pyridin-2-yl)-N-(3-(trifluoromethyl)phenyl)-1H-pyrazole-1-carboxamide (CAS 303995-19-9)
- 4-Hydrazino-2-phenylquinazoline (CAS 6484-29-3)
- 9-(4-Bromophenyl)-5,6,7,9-tetrahydro-[1,2,4]triazolo[5,1-b]quinazolin-8(4H)-one (CAS 385787-35-9)
- 1,1',1''-(((1,3,5-triazine-2,4,6-triyl)tris(oxy))tris(benzene-4,1-diyl))tris(ethan-1-one) (CAS 1919-15-9)
- 4-Chloro-2-[(1E)-{[2-(1H-indol-3-yl)ethyl]imino}methyl]phenol (CAS 299420-52-3)
- Tau Peptide (45-73) (Exon 2/Insert 1 Domain) trifluoroacetate salt (CAS 2022956-54-1)
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