4-Hydroxy-17β-estradiol CAS 5976-61-4
| CAS No. | 5976-61-4 |
| Molecular Formula | C18H24O3 |
| Molecular Weight | 288.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 288.38 g/mol gives 4-Hydroxy-17β-estradiol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-Hydroxy-17β-estradiol (CAS 5976-61-4), molecular formula C18H24O3 and molecular weight 288.38 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C18H24O3, 4-Hydroxy-17β-estradiol contains a steroid core, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 288.38 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Hydroxy-17β-estradiol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H24O3 |
| Molecular Weight | 288.38 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
Related Hydroxy Standards
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Recommended Standards
- 2-Hydroxyestradiol (CAS 362-05-0)
- Milnacipran impound 35 (CAS 105310-24-5)
- 4-(ethoxy(phenyl)methyl)-1,1'-biphenyl (CAS 2137934-65-5)
- Milnacipran impurity 38 (CAS CATO-C4X-103338)
- Lithium 7-fluoro-1-(tetrahydro-2h-pyran-4-yl)-1h-benzo[d]imidazole-2-carboxylate (CAS 2197053-84-0)
- 2-(Allylthio)-4-(thiophen-2-yl)pyrimidine (CAS 685107-86-2)
- Sodium 6,6'-((((2,4-dihydroxy-1,3-phenylene)bis(diazene-2,1-diyl))bis(4,1-phenylene))bis(azanediyl))bis(3-nitrobenzenesulfonate) (CAS 71799-43-4)
- 3-[(3-Methoxybenzyl)oxy]pyrrolidine hydrochloride (CAS 1220034-35-4)
- 2-[(1h-indazol-5-yl)formamido]propanoic acid (CAS 1396973-36-6)
- 3-Bromo-2-methyl-4-quinolinol (CAS 65673-88-3)
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- Methyl 6-amino-3-bromo-5-fluoropicolinate (CAS 2891457-46-6)
- 1,3,4-Oxadiazol-2(3H)-one (CAS 51517-09-0)
- ((Cys31,Nva34)-Neuropeptide Y (27-36))2 (CAS 172997-92-1)
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