Clemastine EP Impurity C CAS 59767-24-7
| CAS No. | 59767-24-7 |
| Molecular Formula | C14H13ClO |
| Molecular Weight | 232.71 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Clemastine EP Impurity C is closely related to a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Clemastine EP Impurity C (CAS 59767-24-7, C14H13ClO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system, Clemastine EP Impurity C is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 232.71 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Clemastine EP Impurity C under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H13ClO |
| Molecular Weight | 232.71 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | Cl-containing |
Related Clemastine Standards
- Clemastine Impurity 12 (CAS CATO-C4X-183712)
- Clemastine Impurity 27 (CAS 10095-17-7)
- Clemastine Impurity 28 (CAS 1333340-87-6)
- Clemastine Impurity 29 (CAS 94511-39-4)
- Clemastine Impurity 30 (CAS CATO-C4X-183730)
- Clemastine Impurity 17 (CAS CATO-C4X-183717)
- Clemastine Impurity 31 (CAS CATO-C4X-183731)
- Clemastine Fumarate Impurity 1 (CAS 599-67-7)
Recommended Standards
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- Vilazodone impurity 18 (CAS CATO-C4X-135518)
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- (2-Chloro-benzyl)-pyridin-2-ylmethyl-amine 680185-71-1 8013AE C13H13ClN2 (CAS 680185-71-1)
- Esmolol Impurity 49 (CAS CATO-C4X-189149)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com