Diethyl 2,3-diethylmaleate CAS 59863-62-6
| CAS No. | 59863-62-6 |
| Molecular Formula | C12H20O4 |
| Molecular Weight | 228.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Diethyl 2,3-diethylmaleate.
Diethyl 2,3-diethylmaleate (CAS 59863-62-6), molecular formula C12H20O4 and molecular weight 228.28 g/mol, is a CATO reference standard with documented purity and traceability.
Diethyl 2,3-diethylmaleate (C12H20O4) contains a carboxylic acid group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H20O4 |
| Molecular Weight | 228.28 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1974 |
Related Diethyl Standards
- Diethyl (1R,2S)-cyclohexane-1,2-dicarboxylate (CAS 17351-07-4)
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- 1,3-Diethyl 2-cyclopentylpropanedioate (CAS 18928-91-1)
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- Diethyl (1r,4r)-cyclohexane-1,4-dicarboxylate (CAS 19145-96-1)
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Recommended Standards
- Diethyl 2,2'-(cyclobutane-1,1-diyl)diacetate (CAS 51008-00-5)
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- Diethyl 2-(cyclobutylmethyl)malonate (CAS 21782-47-8)
- Diethyl cyclohexane-1,4-dicarboxylate (CAS 72903-27-6)
- 1-Hydroxymethyl-2-oxadamantane (CAS 1303974-14-2)
- 4-Methoxynaphthalen-1-yl acetate (CAS 68716-07-4)
- 1-(3,4-Dimethoxybenzyl)-1H-indazol-3(2H)-one (CAS 1229-97-6)
- 4-(Difluoromethyl)-3-hydroxy-6-methylpicolinaldehyde (CAS 1806977-34-3)
- 1-(2-Bromo-4-methylphenyl)-5-oxopyrrolidine-3-carboxylic acid (CAS 1016750-76-7)
- 1-(3,5-Dimethylpyridin-2-yl)cyclopropan-1-amine (CAS 1266203-58-0)
- 3-Ethoxy-N-propylspiro[3.4]Octan-1-amine hydrochloride (CAS 1333847-63-4)
- 2-Oxo-4-(pyridin-4-yl)-1,2-dihydropyrimidine-5-carboxylic acid hydrate (CAS 690631-95-9)
- 6-Bromo-4-fluoro-1,2-dihydro-3H-indazol-3-one (CAS 887568-01-6)
- Semaglutide impurity 89 (CAS CATO-C4X-222689)
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