methyl 1-[4-(chlorosulfonyl)phenyl]cyclopropane-1-carboxylate CAS 600134-92-7
| CAS No. | 600134-92-7 |
| Molecular Formula | C11H11ClO4S |
| Molecular Weight | 274.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of methyl 1-[4-(chlorosulfonyl)phenyl]cyclopropane-1-carboxylate (C11H11ClO4S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
methyl 1-[4-(chlorosulfonyl)phenyl]cyclopropane-1-carboxylate (CAS 600134-92-7) is a high-purity analytical reference standard with the molecular formula C11H11ClO4S and a molecular weight of 274.72 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), methyl 1-[4-(chlorosulfonyl)phenyl]cyclopropane-1-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H11ClO4S |
| Molecular Weight | 274.72 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
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- Brovudine Dimer Impurity 11 (CAS CATO-C4X-275811)
- Semaglutide Impurity 166 (CAS 1395881-03-4)
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