3-(4-Hydroxybenzylidene)imidazo[1,2-c]quinazolin-2(3H)-one CAS 60045-38-7
| CAS No. | 60045-38-7 |
| Molecular Formula | C17H11N3O2 |
| Molecular Weight | 289.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(4-Hydroxybenzylidene)imidazo[1,2-c]quinazolin-2(3H)-one (C17H11N3O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 3-(4-Hydroxybenzylidene)imidazo[1,2-c]quinazolin-2(3H)-one (CAS 60045-38-7), a certified reference material (molecular formula C17H11N3O2, MW 289.29 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H11N3O2 |
| Molecular Weight | 289.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Nitrogen Atoms | 3 |
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- 5-(3-Hydroxybenzylidene)-2-(piperazin-1-yl)thiazol-4(5H)-one (CAS 941897-42-3)
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- (E)-2-((2-hydroxybenzylidene)amino)-5-phenylfuran-3-carbonitrile (CAS 325809-26-5)
- (Z)-5-(4-Hydroxybenzylidene)-3-isobutyl-2-thioxothiazolidin-4-one (CAS 1558598-41-6)
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Recommended Standards
- 3-(4-(Hydroxymethyl)-3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidine-2,6-dione (CAS 2408504-64-1)
- 3-(4-Nitrophenyl)-4-(pyrrolidin-1-ylmethyl)isoxazol-5(2H)-one (CAS 61194-98-7)
- 3-(4-(4-Nitrophenyl)piperazin-1-yl)-1H-1,2,4-triazol-5-amine (CAS 339021-30-6)
- 3-[(3,5-dimethyl-4-nitro-1h-pyrazol-1-yl)methyl]-4-methoxybenzaldehyde (CAS 514800-77-2)
- (2-(4-Fluorophenyl)oxazol-4-yl)methanamine (CAS 885272-89-9)
- N-Desmethyl N-Nitroso Tramadol (Mixture of Enantiomers) (CAS CATO-C4X-149814)
- Acetylatractylodinol (CAS 61582-39-6)
- 2-(Cyclopropylamino)-2-(pyridin-4-yl)propanamide dihydrochloride (CAS 1423026-74-7)
- (2,6-Dibromo-3-methoxyphenyl)boronic acid (CAS 850567-93-0)
- N-(2-(2,5-Dichlorophenyl)benzo[d]oxazol-5-yl)-3-methyl-4-nitrobenzamide (CAS 314029-53-3)
- 4-(Furan-2-ylmethylene)-1,2,3,4-tetrahydroacridine-9-carboxylic acid (CAS 22311-71-3)
- 3-Acetamido-5-bromopicolinic acid (CAS 1820704-68-4)
- 2-Hydroxy-5-Methyl-4-Oxohexanoic Acid (CAS 89966-33-6)
- Semaglutide impurity 84 (CAS CATO-C4X-222684)
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