3-(3-(Trifluoromethyl)phenyl)pyrrolidine-2,5-dione CAS 60050-38-6
| CAS No. | 60050-38-6 |
| Molecular Formula | C11H8F3NO2 |
| Molecular Weight | 243.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 243.18 g/mol gives 3-(3-(Trifluoromethyl)phenyl)pyrrolidine-2,5-dione distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-(3-(Trifluoromethyl)phenyl)pyrrolidine-2,5-dione (CAS 60050-38-6) is a high-purity analytical reference standard with the molecular formula C11H8F3NO2 and a molecular weight of 243.18 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 3-(3-(Trifluoromethyl)phenyl)pyrrolidine-2,5-dione is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 243.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-(3-(Trifluoromethyl)phenyl)pyrrolidine-2,5-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H8F3NO2 |
| Molecular Weight | 243.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethyl Standards
- Methyl 2-(trifluoromethyl)-1H-indole-3-carboxylate (CAS 1008365-18-1)
- Methyl 4-(trifluoromethyl)-1H-indole-2-carboxylate (CAS 1098340-27-2)
- 3a-(Trifluoromethyl)-3,3a-dihydrobenzo[d]pyrrolo[2,1-b]oxazol-1(2H)-one (CAS 1191903-98-6)
- 8-(Trifluoromethyl)-2,3,4,5-tetrahydro-1H-1-benzazepine-2,5-dione (CAS 1228960-85-7)
- 1-Methyl-5-(trifluoromethyl)-1H-indole-2-carboxylic Acid (CAS 1257092-36-6)
- 1-Methyl-6-(trifluoromethyl)-1H-indole-3-carboxylic acid (CAS 1257120-17-4)
- 2-[2-(trifluoromethyl)-1h-indol-3-yl]acetic acid (CAS 132502-93-3)
- Methyl 6-(trifluoromethyl)-1H-indole-4-carboxylate (CAS 1352905-52-2)
Recommended Standards
- 2-Methyl-6-(trifluoromethoxy)quinolin-4-ol (CAS 927800-79-1)
- 3,3,3-Trifluoro-2-(1h-indol-3-yl)propanoic acid (CAS 250339-41-4)
- 2-Methyl-4-(3-(trifluoromethyl)phenyl)isoxazol-5(2H)-one (CAS 62451-87-0)
- 3-Methyl-5-(trifluoromethyl)-1H-indole-2-carboxylic acid (CAS 854531-37-6)
- Dimethyl-1,4-Phenylenediacrylate (CAS 23746-55-6)
- (1,1,3-Trimethylbutyl)amine (CAS 64379-30-2)
- (4-Fluorophenyl)acetic acid hydrazide (CAS 34547-28-9)
- 2-[(2-oxo-4-phenyl-2h-chromen-7-yl)oxy]acetic acid (CAS 130181-72-5)
- 7-(2-Cyclohexylethyl)-6-(hydroxymethyl)-7H-pyrrolo[2,3-d]pyrimidine-2-carbonitrile (CAS 1059174-71-8)
- tert-Butyl (5-(1-formylpyrrolidin-2-yl)pyridin-2-yl)(isopropyl)carbamate (CAS 1352489-82-7)
- 2-Butylamino-6-chloropyrazine (CAS 951884-06-3)
- 1-(Tetrahydro-2H-pyran-4-yl)ethanamine hydrochloride (CAS 1363404-80-1)
- 3-bromo-2-ethyl-5-(propan-2-yl)pyrazolo[1,5-a]pyrimidin-7-amine (CAS 2905749-85-9)
- Insulin Degludec Impurity 28 (CAS CATO-C4X-215728)
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