1-(2-Hydroxy-5-methylphenyl)-3-(4-chlorophenyl)-1,3-propanedione CAS 60402-29-1

Purity 97%+In StockPharmaceutical Standards
CAS No.60402-29-1
Molecular FormulaC16H13ClO3
Molecular Weight288.73 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(2-Hydroxy-5-methylphenyl)-3-(4-chlorophenyl)-1,3-propanedione CAS 60402-29-1 chemical structure

Description

The molecular framework of 1-(2-Hydroxy-5-methylphenyl)-3-(4-chlorophenyl)-1,3-propanedione (C16H13ClO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

1-(2-Hydroxy-5-methylphenyl)-3-(4-chlorophenyl)-1,3-propanedione (CAS 60402-29-1) is a high-purity analytical reference standard with the molecular formula C16H13ClO3 and a molecular weight of 288.73 g/mol.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 1-(2-Hydroxy-5-methylphenyl)-3-(4-chlorophenyl)-1,3-propanedione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC16H13ClO3
Molecular Weight288.73 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1974
Halogen ContentCl-containing

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