10-Hydroxynaltrexone CAS 604767-82-0

Purity >95%In StockPharmaceutical Standards
CAS No.604767-82-0
Molecular FormulaC20H23NO5
Molecular Weight357.40 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

10-Hydroxynaltrexone CAS 604767-82-0 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

10-Hydroxynaltrexone (CAS 604767-82-0), molecular formula C20H23NO5 and molecular weight 357.40 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, 10-Hydroxynaltrexone is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 357.40 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC20H23NO5
Molecular Weight357.40 g/mol
AppearancePale yellow to yellow crystalline powder
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1985
Nitrogen Atoms1

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