4-(4-Fluorobicyclo[2.2.2]Octan-1-yl)aniline CAS 60526-67-2
| CAS No. | 60526-67-2 |
| Molecular Formula | C14H18FN |
| Molecular Weight | 219.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(4-Fluorobicyclo[2.2.2]Octan-1-yl)aniline.
4-(4-Fluorobicyclo[2.2.2]Octan-1-yl)aniline (CAS 60526-67-2), molecular formula C14H18FN and molecular weight 219.30 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(4-Fluorobicyclo[2.2.2]Octan-1-yl)aniline (C14H18FN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H18FN |
| Molecular Weight | 219.30 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluorobicyclo Standards
- 2-(3-Fluorobicyclo[1.1.1]Pentan-1-yl)-4,4-dimethylcyclohex-1-ene-1-carbonitrile (CAS 2306264-97-9)
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- (4-(3-Fluorobicyclo[1.1.1]Pentan-1-yl)phenyl)methanol (CAS 1934767-33-5)
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