6-(Benzyloxy)-2,4-dichloro-7-methoxyquinazoline CAS 60548-01-8

Purity 97%+In StockPharmaceutical Standards
CAS No.60548-01-8
Molecular FormulaC16H12Cl2N2O2
Molecular Weight335.18 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-(Benzyloxy)-2,4-dichloro-7-methoxyquinazoline CAS 60548-01-8 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-(Benzyloxy)-2,4-dichloro-7-methoxyquinazoline.

CATO supplies 6-(Benzyloxy)-2,4-dichloro-7-methoxyquinazoline (CAS 60548-01-8), a certified reference material (molecular formula C16H12Cl2N2O2, MW 335.18 g/mol) for analytical method development and quality control.

The molecular framework of 6-(Benzyloxy)-2,4-dichloro-7-methoxyquinazoline (C16H12Cl2N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 6-(Benzyloxy)-2,4-dichloro-7-methoxyquinazoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC16H12Cl2N2O2
Molecular Weight335.18 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1974
Halogen ContentCl-containing
Nitrogen Atoms2

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