N,N-Dimethyl-2-[[2-Phenyl-8-(Trifluoromethyl)-4-Quinazolinyl]Thio]-Acetamide CAS 606131-37-7
| CAS No. | 606131-37-7 |
| Molecular Formula | C19H16F3N3OS |
| Molecular Weight | 391.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N,N-Dimethyl-2-[[2-Phenyl-8-(Trifluoromethyl)-4-Quinazolinyl]Thio]-Acetamide (CAS 606131-37-7) is a high-purity analytical reference standard with the molecular formula C19H16F3N3OS and a molecular weight of 391.41 g/mol.
The molecular framework of N,N-Dimethyl-2-[[2-Phenyl-8-(Trifluoromethyl)-4-Quinazolinyl]Thio]-Acetamide (C19H16F3N3OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N,N-Dimethyl-2-[[2-Phenyl-8-(Trifluoromethyl)-4-Quinazolinyl]Thio]-Acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H16F3N3OS |
| Molecular Weight | 391.41 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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