1,3-Bis(2-mercaptoethyl)urea CAS 60633-86-5

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1,3-Bis(2-mercaptoethyl)urea.

1,3-Bis(2-mercaptoethyl)urea (CAS 60633-86-5) is a high-purity analytical reference standard with the molecular formula C5H12N2OS2 and a molecular weight of 180.29 g/mol.

The molecular framework of 1,3-Bis(2-mercaptoethyl)urea (C5H12N2OS2) is characterized by an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1,3-Bis(2-mercaptoethyl)urea meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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