Isavuconazole Impurity 237 CAS 60695-12-7
| CAS No. | 60695-12-7 |
| Molecular Formula | C11H11NO2 |
| Molecular Weight | 189.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Isavuconazole Impurity 237 (CAS 60695-12-7) is a certified pharmaceutical impurity reference standard with the molecular formula C11H11NO2 and a molecular weight of 189.21 g/mol.
Based on its molecular formula C11H11NO2, Isavuconazole Impurity 237 contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 189.21 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), Isavuconazole Impurity 237 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H11NO2 |
| Molecular Weight | 189.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Nitrogen Atoms | 1 |
Related Isavuconazole Standards
- Isavuconazole Impurity 86 (CAS 40805-50-3)
- Isavuconazole impurity 73 (CAS CATO-C4X-1236173)
- Isavuconazole Impurity 72 (CAS 192225-36-8)
- Isavuconazole Impurity N12 (CAS 2732924-98-8)
- Isavuconazole Impurity 212 (CAS CATO-C4X-1236212)
- Isavuconazole Impurity 57 (CAS CATO-C4X-123657)
- Isavuconazole Impurity 206 (CAS CATO-C4X-1236206)
- Isavuconazole Impurity 3 (CAS 2734004-61-4)
Recommended Standards
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- Phloroglucinol impurity 53 (CAS CATO-C4X-221753)
- Empagliflozin Impurity 63 (CAS 1360568-68-8)
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