5-(5-Bromo-2-methoxybenzylidene)-2-(p-tolyl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one CAS 606953-64-4
| CAS No. | 606953-64-4 |
| Molecular Formula | C19H14BrN3O2S |
| Molecular Weight | 428.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(5-Bromo-2-methoxybenzylidene)-2-(p-tolyl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one.
5-(5-Bromo-2-methoxybenzylidene)-2-(p-tolyl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one (CAS 606953-64-4) is a high-purity analytical reference standard with the molecular formula C19H14BrN3O2S and a molecular weight of 428.30 g/mol.
The molecular framework of 5-(5-Bromo-2-methoxybenzylidene)-2-(p-tolyl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one (C19H14BrN3O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-(5-Bromo-2-methoxybenzylidene)-2-(p-tolyl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H14BrN3O2S |
| Molecular Weight | 428.30 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Bromo Standards
- 4’-Bromo Ampicillin (CAS 1356019-52-7)
- 3-Bromo-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(triisopropylsilyl)-1H-pyrrole (CAS 1126425-94-2)
- N-(4-Bromo-3-methylphenyl)-5-methyl-11-oxo-5H,5aH,6H,7H,8H,9H,11H-pyrido[2,1-b]quinazoline-3-carboxamide (CAS 1574622-16-4)
- 2-((3-Bromo-9-oxo-9H-fluoren-2-yl)carbamoyl)cyclohexanecarboxylic acid (CAS 6341-17-9)
- 2-(2-Bromo-6-ethoxy-4-formylphenoxy)-N-(naphthalen-1-yl)acetamide (CAS 832674-12-1)
- 7-Bromo-5-methyl-N-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)benzo[e][1,2,4]triazin-3-amine (CAS 1245646-89-2)
- 2-Bromo-4-formyl-6-methoxyphenyl 4-acetamidobenzenesulfonate (CAS 1432436-62-8)
- 5-Bromo-2-(4-fluorophenyl)-6-(methylsulfonamido)benzofuran-3-carboxylic acid (CAS 1333244-32-8)
Recommended Standards
- Methyl 3-(4-bromophenyl)-3-(4-methoxybenzenesulfonamido)propanoate (CAS 383148-23-0)
- tert-Butyl 3-(2,7-dichloro-8-fluoropyrido[4,3-d]pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]octane-8-carboxylate (CAS 2454397-98-7)
- N-(2-(2-Bromoacetyl)-4,5-dimethoxyphenyl)-4-methylbenzenesulfonamide (CAS 886493-98-7)
- 1-((4-Iodophenyl)sulfonyl)-4-phenylpiperazine (CAS 309272-60-4)
- 2-(4-chlorophenyl)sulfanyl-N-(4-methoxyphenyl)propanamide 2-[(4-chlorophenyl)thio]-N-(4-methoxyphenyl)propanamide 5730-78-9 A831384 (CAS 5730-78-9)
- 3-(Bromomethyl)-4-iodo-1,5-dimethyl-1H-pyrazole (CAS 1668553-18-1)
- N-(4-Cyclohexylphenyl)-4-isopropylaniline (CAS 886365-92-0)
- Ethyl 3-(N-(furan-2-ylmethyl)-3,4-dimethoxyphenylsulfonamido)propanoate (CAS 185300-64-5)
- Methyl 3,3-Difluorocyclopentanecarboxylate (CAS 1394129-94-2)
- 3-(4-Methylthiophen-2-yl)-5,6-dihydro-4H-pyrrolo[3,2-d]isoxazole (CAS 603068-10-6)
- 1-(2,2-Difluoroethyl)-N-((1,3-dimethyl-1H-pyrazol-4-yl)methyl)-1H-pyrazol-4-amine hydrochloride (CAS 1856040-67-9)
- 2-Cyclopropoxy-3-isopropyl-N-methylbenzamide (CAS 1243374-28-8)
- 2-(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)acetohydrazide (CAS 6535-95-1)
- [Glu]17-Semaglutide (CAS CATO-CPTD788604)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com