4-methylpiperazine-2,6-dione CAS 60725-35-1
| CAS No. | 60725-35-1 |
| Molecular Formula | C5H8N2O2 |
| Molecular Weight | 128.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-methylpiperazine-2,6-dione (CAS 60725-35-1) is a high-purity analytical reference standard with the molecular formula C5H8N2O2 and a molecular weight of 128.13 g/mol.
4-methylpiperazine-2,6-dione (C5H8N2O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H8N2O2 |
| Molecular Weight | 128.13 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1974 |
| Nitrogen Atoms | 2 |
Related methylpiperazine Standards
- 3-Methylpiperazine-2,6-dione (CAS 1486801-78-8)
- 1-Methylpiperazine-2,3-dione (CAS 59702-29-3)
- 1-methylpiperazine-2,5-dione (CAS 5625-52-5)
- 1-methylpiperazine-2,6-dione (CAS 62828-00-6)
- 3-Methylpiperazine-2,5-dione (CAS 6062-46-0)
- 3-Ethyl-1-methylpiperazine (CAS 1341468-11-8)
- 1-ethyl-2-methylpiperazine (CAS 3366-27-6)
- 2-Ethyl-1-methylpiperazine (CAS 4791-32-6)
Recommended Standards
- 4-Isocyanobenzonitrile (CAS 2980-80-5)
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- 5-((Methylamino)methyl)-1H-1,2,4-triazol-3-ol (CAS 660412-53-3)
- 1-(Oxetan-3-yl)-1H-1,2,3-triazol-4-amine (CAS 1713476-45-9)
- (3S)-2,3-dihydro-1-benzofuran-3,5-diamine (CAS 1259903-48-4)
- 1-(Difluoromethyl)cyclopropane-1-sulfonyl chloride (CAS 2091793-00-7)
- Ethyl 5-chloro-1H-pyrrolo[3,2-b]pyridine-3-carboxylate (CAS 2090915-34-5)
- 6-Bromopyridazine-3-carboxamide (CAS 1421313-70-3)
- 2,2-Diacetyl-3-(4-chlorophenyl)-1-(phenylsulfonyl)cyclopropane-1-carbonitrile (CAS 860611-37-6)
- 3-bromo-5-((S)-1-((S)-tert-butylsulfinyl)pyrrolidin-2-yl)pyridine (CAS 2459946-30-4)
- N-(5-chloro-2-methoxyphenyl)-2-((4-phenyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 332376-29-1)
- Upadacitinib Impurity 168 (CAS CATO-C4X-2405168)
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