4-Bromo-5-chlorothiophene-2-carboxylic Acid CAS 60729-37-5
| CAS No. | 60729-37-5 |
| Molecular Formula | C5H2BrClO2S |
| Molecular Weight | 241.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-Bromo-5-chlorothiophene-2-carboxylic Acid (CAS 60729-37-5), molecular formula C5H2BrClO2S and molecular weight 241.49 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Bromo-5-chlorothiophene-2-carboxylic Acid (C5H2BrClO2S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 4-Bromo-5-chlorothiophene-2-carboxylic Acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H2BrClO2S |
| Molecular Weight | 241.49 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | Cl/Br-containing |
| Sulfur Atoms | 1 |
Related Bromo Standards
- 5-bromo-4-chloro-thiophene-2-carboxylic acid (CAS 123418-69-9)
- 2-Bromo-5-chlorothiophene-3-carboxylic acid (CAS 1379306-17-8)
- 4-Bromo-3-chlorothiophene-2-carboxylic acid (CAS 1401992-28-6)
- 3-Bromo-5-chlorothiophene-2-carboxylic acid (CAS 60729-38-6)
- 5-Bromo-3-chlorothiophene-2-carboxylic acid (CAS 842135-76-6)
- 6-bromo-1-chloro-naphthalene (CAS 1000391-24-1)
- 4-Bromo-3-chloro-2-fluorothiophenol (CAS 1160574-65-1)
- 4-Bromo-2-chloro-6-fluorobenzenethiol (CAS 1208074-77-4)
Recommended Standards
- 2,2,2-Trichloro-1-(1,3-dimethyl-1H-pyrazol-4-yl)ethanone (CAS 1306738-48-6)
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- 2,2,2-Trichloro-1-(1,5-dimethyl-1H-pyrazol-4-yl)ethan-1-one (CAS 1306739-77-4)
- 2,6-Di-tert-butyl-4-methylphenol D21 (CAS 64502-99-4)
- 5-(Benzyloxy)-2-bromo-3-chloropyridine (CAS 1335052-36-2)
- Lacidipine (CAS 103890-78-4)
- Diethyl (pyridin-3-ylmethylene)dicarbamate (CAS 2744-17-4)
- 3-(3-Nitrophenyl)-1-phenyl-1h-pyrazole-4-carbaldehyde (CAS 333327-63-2)
- Sodium 2-amino-4-(methylthio)butanoate (CAS 41863-30-3)
- Etoricoxib Impurity 91 (CAS CATO-C4X-108091)
- N-(but-3-yn-1-yl)oxetan-3-amine (CAS 1340195-35-8)
- D-Aspartic Acid beta-Benzyl Ester (CAS 13188-89-1)
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