7-benzyloxy-2,4-dichloro-6-methoxy-quinazoline CAS 60771-18-8
| CAS No. | 60771-18-8 |
| Molecular Formula | C16H28Cl2N2O2 |
| Molecular Weight | 351.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
7-benzyloxy-2,4-dichloro-6-methoxy-quinazoline (CAS 60771-18-8) is a high-purity analytical reference standard with the molecular formula C16H28Cl2N2O2 and a molecular weight of 351.31 g/mol.
The molecular framework of 7-benzyloxy-2,4-dichloro-6-methoxy-quinazoline (C16H28Cl2N2O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 7-benzyloxy-2,4-dichloro-6-methoxy-quinazoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H28Cl2N2O2 |
| Molecular Weight | 351.31 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related benzyloxy Standards
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- (S)-2-(((benzyloxy)carbonyl)amino)-5-(tert-butoxy)-2-methyl-5-oxopentanoic acid (CAS 135923-95-4)
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- 2-((Benzyloxy)methyl)-2-(4-bromophenyl)propane-1,3-diol (CAS 1467061-48-8)
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Recommended Standards
- 4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-1,2,5-oxadiazole-3-carboxylic acid (CAS 2243513-47-3)
- (4-(3-Fluoro-6-methoxy-9H-carbazol-9-yl)butyl)phosphonic acid (CAS CATO-CIM-105786)
- 2'-Deoxy-3',5'-di-O-acetylguanosine (CAS 69992-10-5)
- N-(3-(tert-butyl)-2-methyl-4-oxo-2,4-dihydroindeno[1,2-c]pyrazol-6-yl)-2,2,2-trifluoroacetamide (CAS 1024223-97-9)
- 3-(6-Methylpyridin-2-yl)isoquinolin-1-amine (CAS 66009-87-8)
- 3-Bromo-2-iodofuran (CAS 72167-52-3)
- 4-Chloro-3-fluoro-5-methoxypyridine (CAS 1261473-24-8)
- 4-(Difluoromethyl)-2-iodo-6-methylnicotinaldehyde (CAS 1806019-62-4)
- 4-[(E)-2-(2,3-Dimethoxyphenyl)ethenyl]-1-ethylpyridin-1-ium iodide (CAS 1046808-44-9)
- (2-Bromophenyl)(3-((3-(2-fluorophenyl)-1,2,4-oxadiazol-5-yl)methyl)piperidin-1-yl)methanone (CAS 1705444-18-3)
- [3-(prop-2-yn-1-yloxy)phenyl]methanol (CAS 34905-03-8)
- 3-Nitro-2-phenylthiophene (CAS 18150-94-2)
- (3S)-3-Hydroxy-L-aspartic acid (CAS 7298-99-9)
- Semaglutide impurity 51 (CAS CATO-C4X-222651)
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