| CAS No. | 60792-74-7 |
| Molecular Formula | C7H3ClF3N3O3 |
| Molecular Weight | 269.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Compared with other compounds in its class, the molecular weight of 269.57 g/mol gives N-(4-Chloro-3-nitropyridin-2-yl)-2,2,2-trifluoroacetamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
N-(4-Chloro-3-nitropyridin-2-yl)-2,2,2-trifluoroacetamide (CAS 60792-74-7), molecular formula C7H3ClF3N3O3 and molecular weight 269.57 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-(4-Chloro-3-nitropyridin-2-yl)-2,2,2-trifluoroacetamide (C7H3ClF3N3O3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N-(4-Chloro-3-nitropyridin-2-yl)-2,2,2-trifluoroacetamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
| Molecular Formula | C7H3ClF3N3O3 |
| Molecular Weight | 269.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |