N-(4-Chloro-3-nitropyridin-2-yl)-2,2,2-trifluoroacetamide CAS 60792-74-7

Purity 97%+In StockPharmaceutical Standards
CAS No.60792-74-7
Molecular FormulaC7H3ClF3N3O3
Molecular Weight269.57 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(4-Chloro-3-nitropyridin-2-yl)-2,2,2-trifluoroacetamide CAS 60792-74-7 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 269.57 g/mol gives N-(4-Chloro-3-nitropyridin-2-yl)-2,2,2-trifluoroacetamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

N-(4-Chloro-3-nitropyridin-2-yl)-2,2,2-trifluoroacetamide (CAS 60792-74-7), molecular formula C7H3ClF3N3O3 and molecular weight 269.57 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of N-(4-Chloro-3-nitropyridin-2-yl)-2,2,2-trifluoroacetamide (C7H3ClF3N3O3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures N-(4-Chloro-3-nitropyridin-2-yl)-2,2,2-trifluoroacetamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC7H3ClF3N3O3
Molecular Weight269.57 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO, water
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1974
Halogen ContentF/Cl-containing
Nitrogen Atoms3

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