5-Fluoro-4-methyl-2-(methylsulfonyl)pyrimidine CAS 6090-43-3
| CAS No. | 6090-43-3 |
| Molecular Formula | C6H7FN2O2S |
| Molecular Weight | 190.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
5-Fluoro-4-methyl-2-(methylsulfonyl)pyrimidine (CAS 6090-43-3) is a high-purity analytical reference standard with the molecular formula C6H7FN2O2S and a molecular weight of 190.20 g/mol.
The molecular framework of 5-Fluoro-4-methyl-2-(methylsulfonyl)pyrimidine (C6H7FN2O2S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 5-Fluoro-4-methyl-2-(methylsulfonyl)pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H7FN2O2S |
| Molecular Weight | 190.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Fluoro Standards
- 5-Fluoro-n-methylpyridine-3-sulfonamide (CAS 1249592-68-4)
- 5-fluoro-1H-thieno[2,3-d]pyrimidine-2,4-dione (CAS 2659313-25-2)
- 6-fluoro-1H-thieno[2,3-d]pyrimidine-2,4-dione (CAS 2659313-19-4)
- 4-Fluoro-2-(methylsulfonyl)phenol (CAS 1000339-69-4)
- 4-Fluoro-2-methylbenzenesulfonic acid (CAS 154642-00-9)
- 2-Fluoro-4-methylsulfonylphenol (CAS 398456-87-6)
- 3-Fluoro-4-(methylsulfonyl)phenol (CAS 859538-50-4)
- 4-fluoro-3-methanesulfonylphenol (CAS 2060020-74-6)
Recommended Standards
- 5-Formyl-6-methoxy-2,4-dimethylnicotinonitrile (CAS 531521-30-9)
- 5-Ethyl-3-(hydroxyimino)indolin-2-one (CAS 500711-57-9)
- 5-Hydroxy-4,7-dimethyl-2h-chromen-2-one (CAS 6335-27-9)
- 5-Amino-4-(3-methylpyridin-2-yl)-1H-pyrazol-3(2H)-one (CAS 62019-58-3)
- 1-[(benzyloxy)carbonyl]-4-methoxy-2-methylpyrrolidine-2-carboxylic acid (CAS 2044712-89-0)
- p-Tolyl(5-(p-tolyl)-1H-1,2,4-triazol-3-yl)methanamine (CAS 1707735-85-0)
- Bradykinin acetate salt (CAS 6846-03-3)
- IDO inhibitor 1 (CAS 1668565-74-9)
- 3-Bromo-6-methoxy-2-(trifluoromethyl)pyridine (CAS 1214330-91-2)
- Salbutamol Impurity 135 (CAS CATO-C4X-1176135)
- 2-Ethyl-4-(4-fluorophenyl)thiazole (CAS 324-84-5)
- {3-bromo-2-[2-(diethylamino)ethoxy]phenyl}methanol (CAS 1291743-32-2)
- 4-Chloro-5-(difluoromethyl)-6-methoxynicotinaldehyde (CAS 1805175-37-4)
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