Epinephrine /Adrenaline Impurity 55 CAS 60912-82-5
| CAS No. | 60912-82-5 |
| Molecular Formula | C8H7ClO3 |
| Molecular Weight | 186.59 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 186.59 g/mol gives Epinephrine /Adrenaline Impurity 55 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Epinephrine /Adrenaline Impurity 55 (CAS 60912-82-5) is a certified pharmaceutical impurity reference standard with the molecular formula C8H7ClO3 and a molecular weight of 186.59 g/mol.
The molecular framework of Epinephrine /Adrenaline Impurity 55 (C8H7ClO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H7ClO3 |
| Molecular Weight | 186.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | Cl-containing |
Related Epinephrine Standards
- Epinephrine /Adrenaline Impurity 56 (CAS 25015-92-3)
- rac-Epinephrine-d3 (CAS 1189977-29-4)
- L-(-)-Epinephrine-d3 (CAS 1217733-17-9)
- (±)-Epinephrine-2,5,6,α,β,β-d6 (CAS 1219803-77-6)
- L(-)-Epinephrine (CAS 51-43-4)
- D-(+)-Epinephrine (CAS 150-05-0)
- Epinephrine Impurity 11 (CAS 62322-82-1)
- Epinephrine Impurity 110 (CAS CATO-C4X-1849110)
Recommended Standards
- Adrenaline Impurity 38 (CAS 468721-10-0)
- Glibenclamide Impurity 7 (CAS 3438-16-2)
- 3-Chloro-2,6-dihydroxy-4-methylbenzaldehyde (CAS 57074-21-2)
- Noradrenaline EP Impurity E (CAS 99-40-1)
- Lenvatinib Impurity 59 (CAS CATO-C4X-114059)
- Etoricoxib Impurity 25 (CAS CATO-C4X-108025)
- Tamoxifen Impurity 29 (CAS CATO-C4X-123329)
- 3-Methyl-4-(trifluoromethoxy)picolinonitrile (CAS 886372-31-2)
- 3-(Trifluoromethyl)-4,5-dihydro-1H-indazol-6(7H)-one (CAS 944896-15-5)
- Methyl 2-chloro-4,6-dimethylnicotinate (CAS 339151-88-1)
- 2-(Butylthio)acetimidamide (CAS 105324-30-9)
- 2-Fluoro-4-piperazinobenzoic Acid (CAS 1121613-69-1)
- 4-ethyl-2,3-dihydro-1H-imidazol-2-one (CAS 83962-06-5)
- Tirzepatide Impurity 34 (CAS CATO-C4X-324034)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com