Retapamulin Impurity 1 CAS 60924-38-1
| CAS No. | 60924-38-1 |
| Molecular Formula | C23H36O7S |
| Molecular Weight | 456.59 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Retapamulin Impurity 1.
As a process- or degradation-related impurity, Retapamulin Impurity 1 (CAS 60924-38-1, C23H36O7S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Retapamulin Impurity 1 (C23H36O7S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Retapamulin Impurity 1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H36O7S |
| Molecular Weight | 456.59 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Sulfur Atoms | 1 |
Recommended Standards
- Acotiamide-D6 (CAS 185106-16-5(Unlabelled))
- 2-((5-Benzyl-4-phenyl-4H-1,2,4-triazol-3-yl)thio)-N-(2,6-diethylphenyl)acetamide (CAS 332912-85-3)
- p-Toluenesulfonyloxyandrost-4-ene-3,17-dione-19-d2 (CAS 71995-65-8)
- 2-((5-Benzyl-4-phenyl-4H-1,2,4-triazol-3-yl)thio)-N-(4-butylphenyl)acetamide (CAS 868256-49-9)
- Phytomenadione/Vitamin K1 Impurity 124 (CAS CATO-C4X-2207124)
- Trimebutine impurity 23 (CAS CATO-C4X-185823)
- Metaraminol Impurity 96 (CAS CATO-C4X-225296)
- (1,2-Dimethyl-1H-benzo[d]imidazol-6-yl)boronic acid (CAS 866332-19-6)
- 1,3-Diphenylpropan-1-amine hydrochloride (CAS 5454-35-3)
- {6-Bromopyrazolo[1,5-a]pyrimidin-2-yl}methanol (CAS 1263057-20-0)
- N-({6-[3-(trifluoromethyl)-1H-pyrazol-1-yl]pyridin-3-yl}methylidene)hydroxylamine (CAS 1807797-09-6)
- tert-Butyl (5-(pyrrolidin-2-yl)pyridin-2-yl)carbamate (CAS 1352501-29-1)
- Ethyl tritylglycinate (CAS 18514-46-0)
- Liraglutide-d8 Tetratrifluoroacetate (CAS 204656-20-2 (non-labelled, free base))
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com