6-Methoxy-2,2-bis(trifluoromethyl)chroman-4-ol CAS 609346-77-2
| CAS No. | 609346-77-2 |
| Molecular Formula | C12H10F6O3 |
| Molecular Weight | 316.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6-Methoxy-2,2-bis(trifluoromethyl)chroman-4-ol is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
6-Methoxy-2,2-bis(trifluoromethyl)chroman-4-ol (CAS 609346-77-2), molecular formula C12H10F6O3 and molecular weight 316.20 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C12H10F6O3, 6-Methoxy-2,2-bis(trifluoromethyl)chroman-4-ol contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 316.20 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H10F6O3 |
| Molecular Weight | 316.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
Related Methoxy Standards
- 7-Methoxy-2,2-bis(trifluoromethyl)chroman-4-ol (CAS 609346-78-3)
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- 7-Methoxy-2-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phthalazin-1(2H)-one (CAS 2761059-14-5)
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- 5-Methoxy-2-((3-(trifluoromethyl)benzyl)thio)pyrimidin-4(3H)-one (CAS 338411-00-0)
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Recommended Standards
- 6-Bromo-3-(2-isopropylphenyl)-[1,2,4]triazolo[4,3-a]pyridine (CAS 876301-26-7)
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- Ethyl 2-(3,4-dichlorophenyl)-4-methylthiazole-5-carboxylate (CAS 317319-18-9)
- 4-Chloro-N-(3-chloro-2-methylphenyl)benzenesulfonamide (CAS 7454-70-8)
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