4-(4-Butoxybenzoyl)-5-(4-chlorophenyl)-3-hydroxy-1-(5-methyl-1,3,4-thiadiazol-2-yl)-1H-pyrrol-2(5H)-one CAS 609795-77-9
| CAS No. | 609795-77-9 |
| Molecular Formula | C24H22ClN3O4S |
| Molecular Weight | 483.97 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(4-Butoxybenzoyl)-5-(4-chlorophenyl)-3-hydroxy-1-(5-methyl-1,3,4-thiadiazol-2-yl)-1H-pyrrol-2(5H)-one is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-(4-Butoxybenzoyl)-5-(4-chlorophenyl)-3-hydroxy-1-(5-methyl-1,3,4-thiadiazol-2-yl)-1H-pyrrol-2(5H)-one (CAS 609795-77-9), molecular formula C24H22ClN3O4S and molecular weight 483.97 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, 4-(4-Butoxybenzoyl)-5-(4-chlorophenyl)-3-hydroxy-1-(5-methyl-1,3,4-thiadiazol-2-yl)-1H-pyrrol-2(5H)-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 483.97 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-(4-Butoxybenzoyl)-5-(4-chlorophenyl)-3-hydroxy-1-(5-methyl-1,3,4-thiadiazol-2-yl)-1H-pyrrol-2(5H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H22ClN3O4S |
| Molecular Weight | 483.97 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Butoxybenzoyl Standards
- 4-(4-Butoxybenzoyl)-5-(3-chlorophenyl)-3-hydroxy-1-(5-methyl-1,3,4-thiadiazol-2-yl)-1H-pyrrol-2(5H)-one (CAS 609795-68-8)
- 4-(4-Butoxybenzoyl)-5-(4-ethylphenyl)-3-hydroxy-1-(5-methyl-1,3,4-thiadiazol-2-yl)-1H-pyrrol-2(5H)-one (CAS 609796-74-9)
- 4-(4-Butoxybenzoyl)-3-hydroxy-5-(4-isopropylphenyl)-1-(5-methyl-1,3,4-thiadiazol-2-yl)-1H-pyrrol-2(5H)-one (CAS 609795-69-9)
- 4-(4-Butoxybenzoyl)-5-(4-ethoxyphenyl)-3-hydroxy-1-(5-methyl-1,3,4-thiadiazol-2-yl)-1H-pyrrol-2(5H)-one (CAS 609795-75-7)
- 4-(4-Butoxybenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1-(5-methyl-1,3,4-thiadiazol-2-yl)-1H-pyrrol-2(5H)-one (CAS 609795-73-5)
- 4-(4-Butoxybenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(5-methyl-1,3,4-thiadiazol-2-yl)-1H-pyrrol-2(5H)-one (CAS 617695-21-3)
- 4-(4-Butoxybenzoyl)-3-hydroxy-1-(5-methyl-1,3,4-thiadiazol-2-yl)-5-(p-tolyl)-1H-pyrrol-2(5H)-one (CAS 609795-42-8)
- 4-((4-Butoxybenzoyl)oxy)phenyl (4-butoxyphenyl) oxalate (CAS 108802-34-2)
Recommended Standards
- 3-(4-(2-(4-(5-chloro-2-fluorophenyl)piperazin-1-yl)ethyl)-3-methyl-1H-indazol-1-yl)piperidine-2,6-dione (CAS CATO-C3D-263207)
- (E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-ethoxyquinazolin-6-yl)-4-(piperidin-1-yl)but-2-enamide (Dacomitinib Impurity) (CAS 869199-69-9)
- Metoclopramide Impurity 122 (CAS CATO-C4X-1415122)
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- Hexadecanedioic Acid Related Compound 1 (CAS 843666-28-4)
- 7-Ethyl-2-oxoindoline-5-carboxylic acid (CAS 1225693-10-6)
- 4-[4-(Pyrrolidin-2-ylmethoxy)benzoyl]morpholinehydrochloride (CAS 1332529-62-0)
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- n-(4-Bromophenyl)-3,4-dichlorobenzenesulfonamide (CAS 1902-15-4)
- Ethyl 2-(3-bromophenyl)sulfanylacetate (CAS 141819-40-1)
- 2-Isopropyltetrahydro-2H-pyran-3-carboxylic acid (CAS 1462238-06-7)
- tert-Butyl 3-((4-methylpyridin-2-yl)oxy)piperidine-1-carboxylate (CAS 954228-61-6)
- 5-Hydroxy-1-methylindolin-2-one (CAS 6062-24-4)
- Glucagon (1-29) (CAS 16941-32-5)
Why CATO?
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