Ethyl 2-(2-aminophenyl)acetate hydrochloride CAS 61-88-1
| CAS No. | 61-88-1 |
| Molecular Formula | C10H13NO2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Ethyl 2-(2-aminophenyl)acetate hydrochloride (CAS 61-88-1), molecular formula C10H13NO2HCl and molecular weight 215.68 g/mol, is a CATO reference standard with documented purity and traceability.
Ethyl 2-(2-aminophenyl)acetate hydrochloride (C10H13NO2HCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Ethyl 2-(2-aminophenyl)acetate hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H13NO2 HCl |
| Molecular Weight | 215.68 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- 4-((4-Aminophenyl)thio)phenol (CAS 100062-94-0)
- 1-(4-Aminophenyl)-3-cyclopropylurea (CAS 1000931-26-9)
- n-(3-Aminophenyl)-1-methyl-1h-pyrazole-3-carboxamide (CAS 1001500-68-0)
- 4-(4-Aminophenyl)tetrahydro-2H-pyran-4-ol (CAS 1002726-77-3)
- 1-(4-Aminophenyl)-4-methylpiperidin-4-ol (CAS 1002726-91-1)
- 2-((4-Aminophenyl)thio)acetamide (CAS 100377-22-8)
- Ethyl 3-(3-Aminophenyl)propionate (CAS 10039-64-2)
- N-(4-aminophenyl)-1-ethyl-1H-pyrazole-3-carboxamide (CAS 1004194-64-2)
Recommended Standards
- (S)-6-((S)-2-hydroxy-6-methylhept-5-en-2-yl)-3-methylcyclohex-2-en-1-one (CAS 95602-94-1)
- 1-(4-Bromobutyl)-3-fluorobenzene (CAS 1343688-24-3)
- N-Cyclohexyl-5-phenyl-7-(p-tolyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (CAS 477232-86-3)
- (Meso-1R,5S,6S)-tert-butyl 6-(2-aminoethyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate (CAS 1330765-38-2)
- 5-Bromotetracene (CAS 23790-75-2)
- 1'-Methyl-[1,4'-bipiperidine]-3-carboxylic acid (CAS 856438-17-0)
- 5-Isobutoxypentane-1-sulfonyl chloride (CAS 1342844-50-1)
- 2-((tert-Butoxycarbonyl)amino)-3-(2,3-dimethylphenyl)propanoic acid (CAS 1259979-17-3)
- 4-(Chloromethyl)-1-naphthonitrile (CAS 112929-87-0)
- Semaglutide impurity 24 (CAS CATO-C4X-222624)
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