2-Bromo-3-chloropyridin-4-amine CAS 610277-13-9
| CAS No. | 610277-13-9 |
| Molecular Formula | C5H4BrClN2 |
| Molecular Weight | 207.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Bromo-3-chloropyridin-4-amine is closely related to a nitrile group, chlorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-Bromo-3-chloropyridin-4-amine (CAS 610277-13-9), molecular formula C5H4BrClN2 and molecular weight 207.46 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrile group, chlorine/bromine substitution, 2-Bromo-3-chloropyridin-4-amine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 207.46 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Bromo-3-chloropyridin-4-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H4BrClN2 |
| Molecular Weight | 207.46 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 6-Bromo-5-chloropyridin-2-amine (CAS 1004294-58-9)
- 2-Bromo-6-chloropyridin-3-amine (CAS 1050501-88-6)
- 2-Bromo-6-chloropyridin-4-amine (CAS 1060815-59-9)
- 2-Bromo-5-chloropyridin-4-amine (CAS 1060815-72-6)
- 6-Bromo-3-chloropyridin-2-amine (CAS 1060815-73-7)
- 4-Bromo-2-chloro-6-methylpyrimidine (CAS 1137576-45-4)
- 4-Bromo-6-chloropyridin-2-amine (CAS 1206250-19-2)
- 2-Bromo-5-chloro-3-methylpyrazine (CAS 1260664-82-1)
Recommended Standards
- 2-Amino-5-bromo-4-chloropyridine (CAS 942947-94-6)
- 2-Bromo-4-chloro-6-methylpyrimidine (CAS 89283-93-2)
- 2-Amino-5-bromo-3-chloropyridine (CAS 38185-55-6)
- 2-Bromo-4-chloropyridin-3-amine (CAS 357263-45-7)
- (R)-2-amino-3-(4-chloro-3-(trifluoromethyl)phenyl)propanoic acid (CAS 792871-31-9)
- 2-Bromo-N-(5-ethyl-1,3,4-thiadiazol-2-yl)propanamide (CAS 898730-82-0)
- 2-Amino-3-(trifluoromethyl)isonicotinaldehyde (CAS 1227582-07-1)
- Tetrahydro-2,2,6,6-tetramethyl-2H-pyran-4-amine (CAS 1301178-43-7)
- 4-{[1-(6-Chloropyridazin-3-yl)piperidin-4-yl]carbonyl}morpholine (CAS 1197597-95-7)
- (S)-N-(3-Methyl-1-(phenylselanyl)butan-2-yl)benzamide (CAS 869383-47-1)
- 2-Chloro-3-(2-chloro-6-methylphenyl)-1-propene (CAS 951895-29-7)
- N-(3-Methoxyphenyl)-5-methyl-12-oxo-5H,5aH,6H,7H,8H,9H,10H,12H-azepino[2,1-b]quinazoline-3-carboxamide (CAS 1775409-11-4)
- 7-azaspiro[3.5]nonane hydrochloride (CAS 1414885-16-7)
- D-[Phe]6-Semaglutide (CAS CATO-CPTD788633)
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