4-(2-Fluorophenyl)-2-fluorophenol CAS 612092-34-9
| CAS No. | 612092-34-9 |
| Molecular Formula | C12H8F2O |
| Molecular Weight | 206.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-(2-Fluorophenyl)-2-fluorophenol (CAS 612092-34-9) is a high-purity analytical reference standard with the molecular formula C12H8F2O and a molecular weight of 206.19 g/mol.
The molecular framework of 4-(2-Fluorophenyl)-2-fluorophenol (C12H8F2O) is characterized by a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H8F2O |
| Molecular Weight | 206.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
Related Fluorophenyl Standards
- 4-(3-Fluorophenyl)-3-fluorophenol (CAS 1052241-69-6)
- 4-(3-Fluorophenyl)-2-fluorophenol (CAS 1214390-52-9)
- 4-(4-Fluorophenyl)-3-fluorophenol (CAS 349665-92-5)
- Bis(4-fluorophenyl) ether (CAS 330-93-8)
- 5-(2-Fluorophenyl)cyclohexane-1,3-dione (CAS 102821-72-7)
- (5-(4-Fluorophenyl)-2-methylfuran-3-yl)methanol (CAS 111787-93-0)
- 1-(2-Fluorophenyl)-1H-pyrazole-4-carboxylic acid (CAS 1134310-63-6)
- 1-(4-Fluorophenyl)-1H-imidazole-4-carboxylic acid (CAS 114067-97-9)
Recommended Standards
- 4-(2,6-Difluorophenyl)phenol (CAS 628306-32-1)
- 4-(3,5-Difluorophenyl)phenol (CAS 656304-67-5)
- 4-(2,3-Difluorophenyl)phenol (CAS 202464-01-5)
- 4-(3-Methoxyphenyl)-2-oxobut-3-enoic acid (CAS 65152-37-6)
- trans-3-Fluorocyclohexanamine (CAS 1273564-10-5)
- 3-(((1-Hydroxybutan-2-yl)amino)methyl)phenol (CAS 1038236-60-0)
- 1-[[4-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl]-1H-pyrazole (CAS 1486485-41-9)
- (R)-6-Chloro-1,2,3,4-tetrahydronaphthalen-1-amine (CAS 1057246-77-1)
- 1-(3-Aminoazetidin-1-yl)prop-2-en-1-one (CAS 1466131-12-3)
- 8-Tert-Butyl 6-Ethyl 6,7-Dihydro-5H-Imidazo[1,5-A][1,4]Diazepine-6,8(9H)-Dicarboxylate (CAS 1330763-75-1)
- 3-(4-Methoxyphenyl)-3-oxo-2-{2-[4-(trifluoromethyl)phenyl]hydrazono}propanal (CAS 338414-11-2)
- 3-(azidomethyl)-3-ethyloxetane (CAS 169564-69-6)
- 1-(Isobutylthio)-3-methylcyclobutane-1-carboxylic acid (CAS 1482639-58-6)
- Insulin Degludec Impurity 9 (CAS CATO-C4X-21579)
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