5-(Trifluoromethyl)benzo[d]isothiazol-3-amine CAS 613262-18-3
| CAS No. | 613262-18-3 |
| Molecular Formula | C8H5F3N2S |
| Molecular Weight | 218.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(Trifluoromethyl)benzo[d]isothiazol-3-amine.
CATO supplies 5-(Trifluoromethyl)benzo[d]isothiazol-3-amine (CAS 613262-18-3), a certified reference material (molecular formula C8H5F3N2S, MW 218.20 g/mol) for analytical method development and quality control.
The molecular framework of 5-(Trifluoromethyl)benzo[d]isothiazol-3-amine (C8H5F3N2S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-(Trifluoromethyl)benzo[d]isothiazol-3-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5F3N2S |
| Molecular Weight | 218.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Trifluoromethyl Standards
- 6-((Trifluoromethyl)thio)-1H-indazole (CAS 105391-72-8)
- 4-Methyl-6-((trifluoromethyl)thio)nicotinonitrile (CAS 1204234-83-2)
- 4-(Trifluoromethyl)benzo[d]isothiazol-3-amine (CAS 1379356-60-1)
- (R)-2-(Trifluoromethyl)pyrrolidine-1-sulfonamide (CAS 1389310-03-5)
- (S)-1-((Trifluoromethyl)sulfonyl)pyrrolidin-3-amine (CAS 1568163-85-8)
- (R)-1-((Trifluoromethyl)sulfonyl)pyrrolidin-3-amine (CAS 1568225-76-2)
- 1-((Trifluoromethyl)sulfonyl)piperazine (CAS 89245-14-7)
- 2-(Trifluoromethyl)benzo[d]thiazol-4-amine (CAS 58460-21-2)
Recommended Standards
- 5-(Thiophen-3-yl)-3-(trifluoromethyl)-1H-pyrazole (CAS 2408886-65-5)
- 5-(Trifluoromethyl)benzo[d]thiazol-2-amine (CAS 60388-38-7)
- 5-(Fluorosulfonyl)-2-methylbenzoic acid (CAS 21346-65-6)
- 5-6-O-Isopropylidene-L-gulonic acid-1-4-lactone (CAS 94697-68-4)
- Ethyl 1,2-diamino-4-(4-(benzyloxy)phenyl)-5-cyano-6-oxo-1,6-dihydropyridine-3-carboxylate (CAS 339100-61-7)
- 3,5-Diphenyl-1H-pyrazol-4-amine (CAS 5272-85-5)
- 2-(5-Formylthiophen-2-yl)benzonitrile (CAS 194416-92-7)
- [3-(propan-2-yl)oxetan-3-yl]methanamine (CAS 1539197-30-2)
- N1,N2-Bis(2,6-dimethylphenyl)ethane-1,2-diamine (CAS 72991-60-7)
- 6-Amino-2-imino-4-phenoxypyrimidin-1(2H)-ol (CAS 84370-86-5)
- 2-Amino-5-fluoro-3-nitropyridine (CAS 212268-12-7)
- rel-(3R,4R)-4-(2,2-Difluoroethoxy)-1-methylpyrrolidin-3-ol (CAS 2368911-04-8)
- N-(2-(6,7-Dimethyl-2-oxo-1,2-dihydroquinolin-3-yl)ethyl)acetamide (CAS 851402-90-9)
- D-γ-Glu20-Side-Tirzepatide (CAS CATO-CPTD788929)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com