8-fluoro-4-hydroxyquinoline-3-carbonitrile CAS 61338-15-6
| CAS No. | 61338-15-6 |
| Molecular Formula | C10H5FN2O |
| Molecular Weight | 188.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 8-fluoro-4-hydroxyquinoline-3-carbonitrile (CAS 61338-15-6), a certified reference material (molecular formula C10H5FN2O, MW 188.16 g/mol) for analytical method development and quality control.
Based on its molecular formula C10H5FN2O, 8-fluoro-4-hydroxyquinoline-3-carbonitrile contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 188.16 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H5FN2O |
| Molecular Weight | 188.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related fluoro Standards
- 7-Fluoro-4-oxo-1,4-dihydroquinoline-3-carbonitrile (CAS 1008780-80-0)
- 6-Fluoro-4-hydroxyquinoline-7-carbonitrile (CAS 1260761-66-7)
- 5-Fluoro-1-(pyridin-2-yl)-1H-pyrazole-4-carbonitrile (CAS 1269293-12-0)
- 5-Fluoro-1-(propan-2-yl)-1,3-diazinane-2,4,6-trione (CAS 1564748-31-7)
- Ethyl 4-fluoro-5-hydroxy-1-methyl-1H-pyrazole-3-carboxylate (CAS 1707364-85-9)
- 3-(1-fluoro-2-methylpropan-2-yl)-1,2,4-oxadiazole-5-carboxylic acid (CAS 2925379-34-4)
- 3-Fluoro-2-(1h-1,2,4-triazol-1-yl)benzonitrile (CAS 870562-65-5)
- 4-Fluoro-3-(oxazol-5-yl)benzonitrile (CAS 2379322-65-1)
Recommended Standards
- 7-Fluoro-4-hydroxyquinoline-3-carbonitrile (CAS 622369-69-1)
- N-(4-fluorophenyl)carbonohydrazonoyl dicyanide (CAS 94853-74-4)
- 6-fluoro-4-oxo-1,4-dihydroquinoline-3-carbonitrile (CAS 71083-60-8)
- 2-(2-(Difluoromethoxy)phenyl)ethan-1-ol (CAS 1000533-82-3)
- 384342-62-5 Petromyzonol-3,7,12,21-tetrasulfate tetrapotassium;[(3R,5R,7R,10S,12S,13R,14S)-10,13-dimethyl-3,7-disulfonatooxy-17-[(2R)-5-sulfonatooxypentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-12-yl] sulfate (CAS 384342-62-5)
- 4-(4-Fluorophenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine (CAS 7271-09-2)
- (R)Tert-butyl 3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-hydroxybutanoate (CAS 161529-14-2)
- N-(4-(Dimethylamino)benzyl)-1-(2-fluoroethyl)-3-methyl-1H-pyrazol-4-amine dihydrochloride (CAS 1856057-87-8)
- Y93032D743 7693-27-8 Magnesium hydride Magnesium dihydride Magnesium hydride (MgH2) EINECS 231-705-3 UNII-Y93032D743 (CAS 7693-27-8)
- 2,3,3-trimethylbutanenitrile (CAS 21101-85-9)
- (Z)-4,4,5,5-Tetramethyl-2-(1-phenylbut-1-en-2-yl)-1,3,2-dioxaborolane (CAS 1217435-93-2)
- Methyl 4-(cyclohexylthio)-3-nitrobenzoate (CAS 340974-13-2)
- 5-(3-Chlorophenoxy)-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carbaldehyde (CAS 282523-36-8)
- Semaglutide impurity 106 (CAS CATO-C4X-2226106)
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