Medroxyprogesterone Impurity 12 CAS 61345-71-9
| CAS No. | 61345-71-9 |
| Molecular Formula | C23H30O5 |
| Molecular Weight | 386.48 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Medroxyprogesterone Impurity 12.
As a process- or degradation-related impurity, Medroxyprogesterone Impurity 12 (CAS 61345-71-9, C23H30O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a flavonoid core, a hydroxyl group, an ether linkage, Medroxyprogesterone Impurity 12 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 386.48 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Medroxyprogesterone Impurity 12 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H30O5 |
| Molecular Weight | 386.48 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
Related Medroxyprogesterone Standards
- Medroxyprogesterone Acetate EP Impurity D (CAS 2242-65-1)
- Medroxyprogesterone Acetate (CAS 71-58-9)
- Medroxyprogesterone Impurity 19 (CAS CATO-C4X-145719)
- Medroxyprogesterone Acetate EP Impurity C (CAS 1076198-22-5)
- Medroxyprogesterone Impurity 15 (CAS CATO-C4X-145715)
- Medroxyprogesterone Impurity 16 (CAS CATO-C4X-145716)
- Medroxyprogesterone Impurity 17 (CAS CATO-C4X-145717)
- Medroxyprogesterone Acetate EP Impurity F (CAS 69688-15-9)
Recommended Standards
- Budesonide Impurity 21 (CAS 85234-64-6)
- Progesterone Impurity 88 (CAS 6723-95-1)
- Spironolactone Impurity 11 (CAS 2537956-65-1)
- Formoterol Impurity 94 (CAS CATO-C4X-152594)
- Ceritinib Impurity 43 (CAS CATO-C4X-104843)
- Zopiclone impurity 28 (CAS 69433-07-4)
- Latanoprost Impurity 22 (CAS 141036-66-0)
- 3,9-Dimethyl-3,9-diazaspiro[5.5]undecane (CAS 93004-48-9)
- 3-Methoxy-5-methylcyclopent-2-en-1-one (CAS 7180-60-1)
- 4-Methyl-6-morpholinonicotinaldehyde (CAS 1355179-12-2)
- N-(2-Bromoethyl)acetamide (CAS 113546-43-3)
- (3aR,5S,6R,6aR)-6-Hydroxy-2,2,6-trimethyltetrahydrofuro[2,3-d][1,3]dioxole-5-carbaldehyde (CAS 132024-67-0)
- Methenamine Impurity 3 (CAS 185309-32-4)
- [β-Asp]9-Semaglutide (CAS CATO-CPTD788605)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com