2-([1,1'-Biphenyl]-4-yl)-2-methyl-1,3-dioxolane CAS 6135-51-9
| CAS No. | 6135-51-9 |
| Molecular Formula | C16H16O2 |
| Molecular Weight | 240.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-([1,1'-Biphenyl]-4-yl)-2-methyl-1,3-dioxolane (CAS 6135-51-9), molecular formula C16H16O2 and molecular weight 240.30 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-([1,1'-Biphenyl]-4-yl)-2-methyl-1,3-dioxolane (C16H16O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H16O2 |
| Molecular Weight | 240.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
Related Biphenyl Standards
- 2-([1,1'-Biphenyl]-3-yl)-2-methylpropanoic acid (CAS 1181608-88-7)
- (4'-MEthyl-[1,1'-biphenyl]-3-yl)methyl acetate (CAS 126485-54-9)
- (4'-Methyl-[1,1'-biphenyl]-4-yl)methyl acetate (CAS 133151-37-8)
- Ethyl 2-([1,1'-biphenyl]-4-yl)acetate (CAS 14062-23-8)
- 1420880-37-0 5-(4'-Methyl-2-biphenyl)tetrazole-d4 (CAS 1420880-37-0)
- (2'-Methyl-[1,1'-biphenyl]-3-yl)methyl acetate (CAS 1998216-01-5)
- (2'-Methyl-[1,1'-biphenyl]-4-yl)methyl acetate (CAS 2044702-44-3)
- (3'-MEthyl-[1,1'-biphenyl]-4-yl)methyl acetate (CAS 2109439-91-8)
Recommended Standards
- 2-((6-Methylthieno[2,3-d]pyrimidin-4-yl)thio)acetic acid (CAS 890014-20-7)
- 2-(1,3-Dimethyl-2,3-dihydro-1H-benzo[d]imidazol-2-yl)phenol (CAS 3652-93-5)
- 2-((3-Fluoropropyl)thio)-5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 861208-12-0)
- 2-(1H-indol-3-yl)-2-(5-methylfuran-2-yl)ethan-1-amine (CAS 881044-99-1)
- Dofetilide Impurity 10 (CAS 1803592-87-1)
- N-(2-{1-[3-(Trifluoromethyl)benzyl]-1H-benzimidazol-2-yl}ethyl)-2-thiophenecarboxamide (CAS 1510834-37-3)
- 3-(3-Amino-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)propanehydrazide (CAS 299962-34-8)
- 1-(3,5-Bis(trifluoromethyl)phenyl)-2,5-dimethyl-1H-pyrrole (CAS 175205-51-3)
- 5-Hydroxy-2,3,7,8-tetrahydrobenzo[g][1,3,6,9,2]tetraoxaphosphacycloundecine 5-oxide (CAS 149300-81-2)
- Clomipramine Impurity 3 (CAS 79752-03-7)
- (E)-4-((3-cyano-6-methyl-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)amino)-4-oxobut-2-enoic acid (CAS 331962-63-1)
- 1-(2,5-Dimethylbenzyl)cyclopropan-1-amine (CAS 1260765-41-0)
- Guanidinium 4-methylbenzenesulfonate (CAS 63144-77-4)
- [a-Glu](Side chain transposition)- Semaglutide (CAS CATO-C4X-2226111)
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