5-Amino-6-chloro-2-isobutylpyrimidine-4(1H)-thione CAS 61457-09-8
| CAS No. | 61457-09-8 |
| Molecular Formula | C8H12ClN3S |
| Molecular Weight | 217.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Amino-6-chloro-2-isobutylpyrimidine-4(1H)-thione (C8H12ClN3S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
5-Amino-6-chloro-2-isobutylpyrimidine-4(1H)-thione (CAS 61457-09-8), molecular formula C8H12ClN3S and molecular weight 217.72 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Amino-6-chloro-2-isobutylpyrimidine-4(1H)-thione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H12ClN3S |
| Molecular Weight | 217.72 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 5-Amino-2-(sec-butyl)-6-chloropyrimidine-4(1H)-thione (CAS 61457-08-7)
- 5-Amino-2-(tert-butyl)-6-chloropyrimidine-4(1H)-thione (CAS 61457-10-1)
- 5-Amino-2-butyl-6-chloropyrimidine-4(1H)-thione (CAS 61457-07-6)
- 3-amino-2-[(2-chloro-6-fluorophenyl)methyl]propan-1-ol (CAS 1017209-82-3)
- 2-[(4-Amino-6-chloro-1,3,5-triazin-2-yl)(ethyl)-amino]-1-ethanol (CAS 856369-95-4)
- 2-Amino-4-(4-chlorophenyl)-1H-pyrrole-3-carbonitrile (CAS 120450-07-9)
- 2-Amino-4-(4-chloro-1h-pyrazol-1-yl)-2-methylbutanoic acid (CAS 1248792-29-1)
- 2-[1-Amino-2-(3-chloro-phenyl)-ethylidene]-malononitrile (CAS 124883-67-6)
Recommended Standards
- 5-Chloro-4-(piperidin-1-ylmethyl)-1,2,3-thiadiazole (CAS 338406-71-6)
- 6-(Butylthio)-2-chloropyrimidin-4-amine (CAS 284681-94-3)
- 6-Chloro-2-(methylthio)-N-propylpyrimidin-4-amine (CAS 261765-64-4)
- 5-(4-Chlorocyclohexyl)-1,3,4-thiadiazol-2-amine (CAS 57235-65-1)
- (1S,2S,4R)-4-(4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-(hydroxymethyl)cyclopentan-1-ol (CAS 1113025-27-6)
- 4-Cyclopropoxy-N-methyl-2-(methylamino)benzamide (CAS 1243448-39-6)
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