Tolnaftate Impurity 1 CAS 61551-82-4
| CAS No. | 61551-82-4 |
| Molecular Formula | C20H12O7S2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Tolnaftate Impurity 1 (CAS 61551-82-4), a pharmacopoeial impurity reference standard (molecular formula C20H12O7S2Na, MW 451.42 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Tolnaftate Impurity 1 (C20H12O7S2Na) is characterized by a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Tolnaftate Impurity 1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H12O7S2 2*Na |
| Molecular Weight | 451.42 g/mol |
| Purity | >85% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Sulfur Atoms | 2 |
Related Tolnaftate Standards
Recommended Standards
- Etomidate Impurity 33 (CAS CATO-C4X-188433)
- rac-Amorolfine Impurity 18 (Mixture of Diastereomers) (CAS CATO-C4X-154218)
- Lorazepam EP Impurity C (CAS 2955-37-5)
- 4-(Furan-2-carbonyl)-5-methyl-2-phenyl-1H-pyrazol-3(2H)-one (CAS 89076-04-0)
- (4-Methylphenethyl)triphenylphosphonium bromide (CAS 63035-49-4)
- Gabapentin Impurity 13 (CAS 1130-32-1)
- (Z)-3-(2-Cyano-4-hydroxyphenyl)acrylic acid (CAS 27514-61-0)
- (S)-2-Amino-N-((2-chlorothiazol-5-yl)methyl)-3-methylbutanamide (CAS 1354017-41-6)
- 1-(2-Methylphenyl)-1-phenylmethanamine hydrochloride (CAS 49703-56-2)
- D-Thr7-Tirzepatide (CAS CATO-CPTD788924)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com