N-(4-Bromo-3-methylphenyl)-5-methylisoxazole-4-carboxamide CAS 61643-47-8

Purity 97%+In StockPharmaceutical Standards
CAS No.61643-47-8
Molecular FormulaC12H11BrN2O2
Molecular Weight295.13 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(4-Bromo-3-methylphenyl)-5-methylisoxazole-4-carboxamide CAS 61643-47-8 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(4-Bromo-3-methylphenyl)-5-methylisoxazole-4-carboxamide.

N-(4-Bromo-3-methylphenyl)-5-methylisoxazole-4-carboxamide (CAS 61643-47-8), molecular formula C12H11BrN2O2 and molecular weight 295.13 g/mol, is a CATO reference standard with documented purity and traceability.

N-(4-Bromo-3-methylphenyl)-5-methylisoxazole-4-carboxamide (C12H11BrN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), N-(4-Bromo-3-methylphenyl)-5-methylisoxazole-4-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H11BrN2O2
Molecular Weight295.13 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1974
Halogen ContentBr-containing
Nitrogen Atoms2

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